M3501
8-Methoxypsoralen
analytical standard
Synonym(s):
8-MOP, 9-Methoxyfuro[3,2-g][1]benzopyran-7-one, Ammoidin, Methoxsalen, Xanthotoxin
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About This Item
Empirical Formula (Hill Notation):
C12H8O4
CAS Number:
Molecular Weight:
216.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
206-066-9
Beilstein/REAXYS Number:
196453
MDL number:
grade
analytical standard
Quality Segment
form
crystals, fibers, powder
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
white to yellow
mp
148-150 °C (lit.)
solubility
H2O: slightly soluble, acetic acid: soluble
application(s)
food and beverages
format
neat
SMILES string
COc1c2OC(=O)C=Cc2cc3ccoc13
InChI
1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
InChI key
QXKHYNVANLEOEG-UHFFFAOYSA-N
Gene Information
rat ... Maoa(29253)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca2+].
Disclaimer
Protect from light.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Muta. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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