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NIST921

Cortisol (Hydrocortisone)

NIST® SRM® 921

Synonym(s):
11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, Cortisol, Reichstein’s substance M, 4-Pregnene-11β,17α,21-triol-3,20-dione, 17-Hydroxycorticosterone, Kendall’s compound F, Hydrocortisone
Empirical Formula (Hill Notation):
C21H30O5
CAS Number:
Molecular Weight:
362.46
Beilstein:
1354819
MDL number:
NACRES:
NA.24

Quality Level

form

solid

packaging

pkg of 1 g

mp

211-214 °C (lit.)

application(s)

pharmaceutical

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

Gene Information

human ... NR3C1(2908)

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General description

This Standard Reference Material is certified as a chemical of known purity. It is intended primarily for use in the calibration and standardization of procedures for cortisol determinations and for routine critical evaluation of the daily working standards used in these procedures. For more information, please refer to the SDS and COA.

SRM 921_cert SRM 921 _SDS

Biochem/physiol Actions

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology

Certificate of Analysis

Certificate of Origin

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