Skip to Content
Merck
CN

P3800000

Proxyphylline

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

7-(β-Hydroxypropyl)theophylline, (1,3-Dimethyl-7-[2-hydroxypropyl]-2,6-dioxopurine), Proxyphylline

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C10H14N4O3
CAS Number:
603-00-9
Molecular Weight:
238.24
MDL number:
MFCD00022833
UNSPSC Code:
41116107
PubChem Substance ID:
329820192
NACRES:
NA.24

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

pharmaceutical primary standard

API family

proxyphylline

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(O)Cn1cnc2N(C)C(=O)N(C)C(=O)c12

InChI

1S/C10H14N4O3/c1-6(15)4-14-5-11-8-7(14)9(16)13(3)10(17)12(8)2/h5-6,15H,4H2,1-3H3

InChI key

KYHQZNGJUGFTGR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Proxyphylline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

涉药品监管产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Dimitrios N Soulas et al.
International journal of pharmaceutics, 427(2), 192-200 (2012-02-15)
In this work we present results on the release kinetics of a water-soluble model drug (proxyphylline) from symmetrical three-layer ABA matrices made from silicone rubber. The ABA matrices, consisting of an inner drug-containing layer, loaded at concentration near the percolation
M V Badiger et al.
Biomaterials, 14(14), 1059-1063 (1993-11-01)
To enable the synthesis of hydrogels containing microporosity, a family of pore generating additives (porogens) were synthesized from poly(ethylene glycols) (PEGs) with different molecular weights using naphthyl acetic acid. The products formed were characterized by UV-vis, differential scanning calorimetry and
M E McNeill et al.
Journal of biomaterials science. Polymer edition, 5(1-2), 111-130 (1993-01-01)
The mechanisms which control the release of dispersed water-soluble drugs from an initially dry hydrogel are complex. The release profile derives from a combination of several contributing factors which may change with time at different rates. It has been possible
Acute intoxication with theophylline, proxyphylline and diprophylline in a 3-month-old infant after rectal application: pharmacokinetic data under hemoperfusion.
N Gordjani et al.
Acta paediatrica Scandinavica, 79(1), 112-114 (1990-01-01)
Dimitrios N Soulas et al.
International journal of pharmaceutics, 408(1-2), 120-129 (2011-02-22)
In this work we present results on the modification of the release kinetics of a water-soluble model drug (proxyphylline) from silicone rubber (SR) matrices by either: (i) the incorporation of inorganic salts acting as osmotically active excipients in single-layer matrices
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service