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P5239

Pinocembrin

Name: Pinocembrin
Brand: SIAL

analytical standard, ≥95.0% (HPLC), solid

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₂O₄

CAS Number:

480-39-7

Molecular Weight:

256.25

NACRES:

NA.24

PubChem Substance ID:

329820219

UNSPSC Code:

41116107

MDL number:

MFCD06858345

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grade

analytical standard

Quality Level

100

assay

≥95.0% (HPLC)

form

solid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

194-195 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC1=C(C(C[C@@H](C2=CC=CC=C2)O3)=O)C3=CC(O)=C1

InChI

1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1

InChI key

URFCJEUYXNAHFI-ZDUSSCGKSA-N

Related Categories

Analytical Chemistry

Phytochemical Standards

Reference Materials

General description

Pinocembrin is a major flavonoid molecule, isolated from a variety of plants such as Euphorbia, Sparattosperma leucanthum, Populus, Eucalyptus, Pinus heartwood, etc. It exhibits antitumor, antimicrobial, anti-inflammatory and antioxidant properties.

Anti-inflammatory.

Application

Pinocembrin has been used as a standard in the determination of pinocembrin in propolis extract, analyzed using ultraviolet-visible spectrophotometry (UV-Vis).

Pinocembrin may be used as an analytical reference standard for the quantification of the analyte in honey samples using capillary electrophoresis technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Disclaimer

Protect from light.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Pinocembrin⁻Lecithin Complex: Characterization, Solubilization, and Antioxidant Activities.

Xu Yang et al.

Biomolecules, 8(2) (2018-06-21)

Pinocembrin is a natural flavonoid compound which is capable of antioxidant, antibacterial, anti-inflammatory, and antineoplastic activities. The present study aimed to enhance the solubility and antioxidant activities of pinocembrin by complex formation with lecithin. The physicochemical characteristics of pinocembrin⁻lecithin complex

Capillary electrophoresis as an alternative to HPLC for determination of honey flavonoids

Delgado.C, et al.

Chromatographia, 38(1-2), 71-78 (1994)

Antiviral activity of pinocembrin against Zika virus replication.

Jia Le Lee et al.

Antiviral research, 167, 13-24 (2019-04-09)

Zika virus (ZIKV) is a mosquito-borne virus that has garnered a lot of attention in recent years, due to the explosive epidemic from 2014 to 2016. Since its introduction in the Americas in late 2014, ZIKV has spread at an

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.

Rui Liu et al.

BMC medicine, 10, 105-105 (2012-09-20)

It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation end products (RAGE) has been implicated in neuronal degeneration associated with this disease.

Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

Rasul A, et al.

BioMed Research International, 2013(1-2), 71-78 (2013)

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Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

Global Trade Item Number

SKU	GTIN
P5239-50MG	04061834377092

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