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Puerarin

analytical standard

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Synonym(s):
8-(β-D-Glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kakonein
Empirical Formula (Hill Notation):
C21H20O9
CAS Number:
3681-99-0
Molecular Weight:
416.38
Beilstein:
64198
MDL number:
MFCD00076007
PubChem Substance ID:
329820231
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

~80% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages
forensics and toxicology
veterinary

format

neat

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)ccc3C(=O)C(=COc23)c4ccc(O)cc4

InChI

1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1

InChI key

HKEAFJYKMMKDOR-VPRICQMDSA-N

Gene Information

mouse ... Aldh1a2(19378) , Maoa(17161)

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Application

Puerarin may be used as a reference standard for the determination of puerarin in rat plasma after administration of puerariae radix isoflavone, using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Lei Wang et al.
PloS one, 14(6), e0218490-e0218490 (2019-06-25)
Growing evidence indicates that the gut microbiota plays a significant role in the pathophysiological processes of obesity and its related metabolic symptoms in the host. Puerarin, an active ingredient in the root of Pueraria lobate has been suggested to have
HPLC method for the determination and pharmacokinetic studies on puerarin in cerebral ischemia reperfusion rat plasma after intravenous administration of puerariae radix isoflavone
Yan B, et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(2), 297-301 (2005)
Jie-Ping Fan et al.
Food chemistry, 135(4), 2299-2306 (2012-09-18)
Ionic liquid (IL) based ultrasonic assisted extraction (ILUAE) was developed for the effective extraction of puerarin from Radix Puerariae Lobatae (RPL). The ILUAE parameters including the type of ILs, IL concentration, RPL amount, ultrasonic power and time were optimized by
Jing-Hua Peng et al.
The Journal of pharmacology and experimental therapeutics, 344(3), 646-654 (2013-01-02)
Puerarin, an isoflavone component extracted from Kudzu (Pueraria lobata), has been demonstrated to alleviate alcohol-related disorders. Our study examined whether puerarin ameliorates chronic alcoholic liver injury through inhibition of endotoxin gut leakage, the subsequent Kupffer cell activation, and endotoxin receptors
Jeevan K Prasain et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(1), 17-23 (2012-11-06)
The incidence of type 2 diabetes and metabolic disease is rapidly increasing, but effective therapies for their prevention and treatment have been poorly tolerated or minimally effective. In this study, chronic administration of kudzu root extract (8 months, 0.2%, w/w
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