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PHR1791

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Ferulic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
trans-Ferulic acid, trans-4-Hydroxy-3-methoxycinnamic acid, Ferulic acid
Linear Formula:
HOC6H3(OCH3)CH=CHCO2H
CAS Number:
537-98-4
Molecular Weight:
194.18
Beilstein:
1570363
EC Number:
208-679-7
MDL number:
MFCD00004400
PubChem Substance ID:
329823615
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to Ph. Eur. Y0001013
traceable to USP 1270311

API family

ferulic acid

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

168-172 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(/C=C/C1=CC(OC)=C(O)C=C1)=O

InChI

1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+

InChI key

KSEBMYQBYZTDHS-HWKANZROSA-N

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

Ferulic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Hydroxycinnamic acid found in plant-based foods. Antioxidant.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB6783 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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HPLC determination of ferulic acid in rat plasma after oral administration of Rhizoma Chuanxiong and its compound preparation.
Li Y and Bi K
Biomedical Chromatography, 17(8), 543-546 (2003)
Qualitative and quantitative analysis of the major constituents in Chinese medicinal preparation Guan-Xin-Ning injection by HPLC?DAD?ESI-MSn.
Ruan M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 59(2), 184-189 (2012)
Simultaneous analysis of glycyrrhizin, paeoniflorin, quercetin, ferulic acid, liquiritin, formononetin, benzoic acid and isoliquiritigenin in the Chinese proprietary medicine Xiao Yao Wan by HPLC.
Xie J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 45(3), 450-455 (2007)
High-performance liquid chromatographic method for the quantification of phenolics in `Chyavanprash?a potent Ayurvedic drug.
Govindarajan R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(2), 527-532 (2007)
Sisir Kumar Barik et al.
The Journal of nutritional biochemistry, 78, 108325-108325 (2020-01-18)
The hypoglycaemic effects of two Ribes sp. i.e., anthocyanin-rich black currants (BC) were compared to green currants (GC), which are low in anthocyanins to establish which compounds are involved in the regulation of postprandial glycaemia. We determined the effect of

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