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About This Item
Empirical Formula (Hill Notation):
C27H22Cl2N4
CAS Number:
Molecular Weight:
473.40
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3/b30-24+
SMILES string
CC(C)\N=C1/C=C2N(c3ccc(Cl)cc3)c4ccccc4N=C2C=C1Nc5ccc(Cl)cc5
InChI key
WDQPAMHFFCXSNU-BGABXYSRSA-N
grade
pharmaceutical primary standard
API family
clofazimine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Clofazimine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Clofazimine--a review.
B Kumar
Indian journal of leprosy, 63(1), 78-92 (1991-01-01)
The pharmacology, metabolism, and chemistry of clofazimine.
R O'Connor et al.
Drug metabolism reviews, 27(4), 591-614 (1995-01-01)
Lamprene (clofazimine) in leprosy. Basic information.
S J Yawalkar et al.
Leprosy review, 50(2), 135-144 (1979-06-01)
Anthony V Pais et al.
Leprosy review, 75(2), 171-176 (2004-07-31)
We report a case with abdominal complications of clofazimine treatment which included blackish discolouration of the lymph nodes, omentum and peritoneum. A 44-year-old female with lepromatous leprosy and a history of adverse reaction to clofazimine 2 years previously, presented with
M R Holdiness
Clinical pharmacokinetics, 16(2), 74-85 (1989-02-01)
Clofazimine is useful in the treatment of Hansen's disease (leprosy) and some dermatological disorders, and is currently being used in drug regimens for patients with human immunodeficiency viral infections who are also infected with Mycobacterium avium complex. After an oral
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