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Merck
CN

Y0000420

Cefotaxime acid

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Cefotaxime

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About This Item

Empirical Formula (Hill Notation):
C16H17N5O7S2
CAS Number:
63527-52-6
Molecular Weight:
455.47
UNSPSC Code:
41116107
EC Number:
264-299-1
NACRES:
NA.24

Key Documents

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Product Name

Cefotaxime acid, European Pharmacopoeia (EP) Reference Standard

SMILES string

[Na+].[s]1c(nc(c1)\C(=N\OC)\C(=N\[C@@H]2[C@@H]3SCC(=C(N3C2=O)C(=O)O)COC(=O)C)\[O-])N

InChI key

AZZMGZXNTDTSME-XJTDMATHSA-M

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m0./s1

grade

pharmaceutical primary standard

API family

cefotaxime

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Related Categories

Application

Cefotaxime acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

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Christine Ferreiro et al.
European journal of pediatrics, 172(9), 1243-1248 (2013-05-17)
The treatment of complicated urinary tract infection in children is still a matter of debate. In our hospital, antimicrobial treatment is initiated intravenously, and the duration of this treatment is adapted according to the results of a Tc-99m dimercaptosuccinic acid
S I Nwadioha et al.
The Nigerian postgraduate medical journal, 20(1), 9-13 (2013-05-11)
To determine the common aetiolog of acute bacterial meningitis in children and their antibiotic susceptibility pattern. A retrospective study with a review of cerebrospinal fluid culture reports of paediatric patients aged 0-15 years, suspected of acute meningitis in the Medical
Suresh Ramasamy et al.
Journal of tropical pediatrics, 60(1), 83-86 (2013-09-26)
To compare the effectiveness of two antibiotic regimens among neonates with late onset sepsis (LOS). This randomized controlled trial conducted in a tertiary care teaching hospital, South India, included 90 babies with LOS. Detailed history, examination and appropriate investigations were
Detection of extended-spectrum β-lactamases and AmpC β-lactamases in Salmonella enterica isolates from patients in Denmark during 2008-2010.
Mia Torpdahl et al.
International journal of antimicrobial agents, 42(4), 371-372 (2013-08-13)
Kurinchi Selvan Gurusamy et al.
The Cochrane database of systematic reviews, 8(8), CD010268-CD010268 (2013-08-21)
Risk of methicillin-resistant Staphylococcus aureus (MRSA) infection after surgery is generally low, but affects up to 33% of patients after certain types of surgery. Postoperative MRSA infection can occur as surgical site infections (SSIs), chest infections, or bloodstream infections (bacteraemia).
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