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Merck
CN

Y0000481

Dibrompropamidine for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dibrompropamidine diisetionate

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About This Item

Empirical Formula (Hill Notation):
C21H30Br2N4O10S2
CAS Number:
Molecular Weight:
722.42
UNSPSC Code:
41116107
NACRES:
NA.24
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SMILES string

[S](=O)(=O)(O)CCO.Brc1c(ccc(c1)\C(=N\[H])\N)OCCCOc2c(cc(cc2)\C(=N\[H])\N)Br

InChI

1S/C17H18Br2N4O2.C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);3H,1-2H2,(H,4,5,6)

InChI key

BZACJASHKPPTKX-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

dibrompropamidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dibrompropamidine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Certificates of Analysis (COA)

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Cosmetic contact lens-related Acanthamoeba keratitis.
James McKelvie et al.
Clinical & experimental ophthalmology, 37(4), 419-420 (2009-07-15)
Allergic contact dermatitis from dibrompropamidine cream.
C Lützow-Holm
Contact dermatitis, 20(2), 160-160 (1989-02-01)
S S Asghar et al.
Biochimica et biophysica acta, 317(2), 539-548 (1973-08-30)
A series of amidino compounds has been investigated for their inhibitory effects on C1s, C1r, and generation of C1s. Diamidines consisting of two amidinophenyl residues linked in para position by a molecular bridge proved to be the strongest competitive inhibitors
Teresa Løvold Berents et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 129(4), 305-307 (2009-02-24)
There is a high incidence of traumatic wounds. Such wounds often become infected which prolongs the wound healing process. Many patients will contact a pharmacy for antiseptic treatment. Various over-the-counter drugs can help as antiseptic treatment; Brulidine is a cream
B Rabanal et al.
Journal of chromatography. B, Biomedical sciences and applications, 738(2), 293-303 (2000-03-16)
A quick, simple and reliable analysis method has been developed in order to determine berenil, phenamidine, diampron and dibromopropamidine by capillary zone electrophoresis in samples of serum and urine. In order to define the operation parameters in CZE, we have

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