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Y0001470

Benzoic acid

Name: Benzoic acid
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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Linear Formula:

C₆H₅COOH

CAS Number:

65-85-0

Molecular Weight:

122.12

Beilstein:

636131

MDL number:

MFCD00002398

PubChem Substance ID:

329831440

NACRES:

NA.24

grade

pharmaceutical primary standard

Agency

Ph. Eur.

vapor density

4.21 (vs air)

vapor pressure

10 mmHg ( 132 °C)

description

API family: benfluorex

API family

mefenamic acid, benfluorex, metronidazole

autoignition temp.

1061 °F

manufacturer/tradename

EDQM

availability

not available in (Sales restrictions may apply)

bp

249 °C (lit.)

mp

121-125 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)c1ccccc1

InChI

1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)

InChI key

WPYMKLBDIGXBTP-UHFFFAOYSA-N

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Analytical Reference Standards

Sigma-Aldrich

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benzoic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

Signal Word

Danger

Hazard Statements

H315 - H318 - H372

Precautionary Statements

P280 - P302 + P352 - P305 + P351 + P338 + P310 - P314

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

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Distinct nucleic acid interaction properties of HIV-1 nucleocapsid protein precursor NCp15 explain reduced viral infectivity.

Wei Wang et al.

Nucleic acids research, 42(11), 7145-7159 (2014-05-13)

During human immunodeficiency virus type 1 (HIV-1) maturation, three different forms of nucleocapsid (NC) protein-NCp15 (p9 + p6), NCp9 (p7 + SP2) and NCp7-appear successively. A mutant virus expressing NCp15 shows greatly reduced infectivity. Mature NCp7 is a chaperone protein

The bacterial degradation of benzoic acid and benzenoid compounds under anaerobic conditions: unifying trends and new perspectives.

D J Elder et al.

FEMS microbiology reviews, 13(4), 441-468 (1994-04-01)

Simple homocyclic aromatic compounds are extremely abundant in the environment and are derived largely from lignin. Such compounds may enter anaerobic environments and several groups of bacteria, exhibiting diverse energy-yielding mechanisms, have evolved the capacity to overcome the thermodynamic stability

The biochemistry and toxicology of benzoic acid metabolism and its relationship to the elimination of waste nitrogen.

G C Tremblay et al.

Pharmacology & therapeutics, 60(1), 63-90 (1993-10-01)

Detoxification of sodium benzoate by elimination as a conjugate with glycine, a nonessential amino acid, provides a pathway for the disposal of waste nitrogen. Since 1979, sodium benzoate has been widely used in the therapeutic regimen to combat ammonia toxicity

Benzoic acid intermediates in the anaerobic biodegradation of phenols.

K L Londry et al.

Canadian journal of microbiology, 38(1), 1-11 (1992-01-01)

Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone.

Bradley S Moore et al.

Journal of natural products, 65(12), 1956-1962 (2002-12-28)

Although phenylpropanoids and flavonoids are common plant natural products, these major classes of biologically active secondary metabolites are largely absent from bacteria. The ubiquitous plant enzymes phenylalanine ammonia-lyase (PAL) and chalcone synthase (CHS) are key biosynthetic catalysts in phenylpropanoid and

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