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Merck
CN

Y0001563

Mesalazine impurity A

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Aminophenol, 4-Hydroxyaniline

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About This Item

Linear Formula:
H2NC6H4OH
CAS Number:
123-30-8
Molecular Weight:
109.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329831485
MDL number:
MFCD00007869
Beilstein/REAXYS Number:
385836

Key Documents

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Product Name

Mesalazine impurity A, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2

SMILES string

Nc1ccc(O)cc1

InChI key

PLIKAWJENQZMHA-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

mesalazine, mesalamine

manufacturer/tradename

EDQM

mp

185-189 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Mesalazine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

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Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

危险化学品
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Soumabha Bag et al.
Analytica chimica acta, 860, 37-42 (2015-02-16)
Ionization of aliphatic and aromatic aldehydes is improved by performing simultaneous chemical derivatization using 4-aminophenol to produce charged iminium ions during paper spray ionization. Accelerated reactions occur in the microdroplets generated during the paper spray ionization event for the tested
Chongming Liu et al.
Journal of mass spectrometry : JMS, 49(8), 692-699 (2014-07-22)
On contrary to the widely accepted conviction that the m/z 93 ion derived from phenol does not react with CO2, we demonstrate that it makes an adduct with CO2 to a small but demonstrable extent. For example, the product-ion mass
Denial Mahata et al.
International journal of biological macromolecules, 69, 5-11 (2014-05-20)
Cardanol is a non-isoprenoic phenolic lipid-mixture of distilled cashew nut shell liquid obtained from Anacardium occidentale. Herein, cardanol is purified from cashew nut shell liquid (CNSL) and synthesized to new compounds with different azo amphiphiles. These synthesized compounds are allowed
Ahmad Aqel et al.
Journal of chromatographic science, 52(3), 201-210 (2013-02-21)
This paper describes the comprehensive fabrication of monolithic materials for use as stationary phases in capillary liquid chromatography. Several columns were synthesized in the confines of 320 µm i.d. fused-silica capillaries by single-step in situ copolymerization of benzyl methacrylate and
Paula Paíga et al.
Journal of pharmaceutical and biomedical analysis, 106, 61-70 (2014-07-09)
An analytical methodology for the simultaneous determination of seven pharmaceuticals and two metabolites belonging to the non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics therapeutic groups was developed based on off-line solid-phase extraction and ultra-high performance liquid chromatography coupled to tandem mass

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