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Merck
CN

Y0001775

Ropinirole for peak identification 1

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Ropinirole hydrochloride, 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride, SKF 101468 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H24N2O · HCl
CAS Number:
91374-20-8
Molecular Weight:
296.84
NACRES:
NA.24
PubChem Substance ID:
329831565
UNSPSC Code:
41116107
MDL number:
MFCD01754173

Key Documents

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Product Name

Ropinirole for peak identification 1, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H,3-4,8-12H2,1-2H3,(H,17,19);1H

SMILES string

Cl.CCCN(CCC)CCc1cccc2NC(=O)Cc12

InChI key

XDXHAEQXIBQUEZ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

ropinirole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815)

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Related Categories

Application

Ropinirole for peak identification 1 EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.
Selective D2 dopamine receptor agonist, antiparkinsonian

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H400

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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