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Merck
CN

137271

MES hydrate

EMPROVE® EVOLVE

Synonym(s):

MES hydrate, 2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C6H13NO4S · xH2O
CAS Number:
1266615-59-1
Molecular Weight:
195.24 (anhydrous basis)
UNSPSC Code:
12161700
MDL number:
MFCD00149409

Key Documents

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InChI key

MIIIXQJBDGSIKL-UHFFFAOYSA-N

InChI

1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2

SMILES string

O.OS(=O)(=O)CCN1CCOCC1

biological source

synthetic

product line

EMPROVE® EVOLVE

form

powder

technique(s)

cell culture | mammalian: suitable

Quality Level

400

pH

5.5-6.7

useful pH range

5.5-6.7

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

storage temp.

2-30°C

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Application

MES is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Packaging

100 g in poly bottle
5, 25, 50 kg in poly drum

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000524762
0000525177
0000526490
0000524372
0000524372

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