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Merck
CN

137274

MES sodium salt

EMPROVE® EVOLVE

Synonym(s):

MES sodium salt, 2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H12NNaO4S
CAS Number:
71119-23-8
Molecular Weight:
217.22
Beilstein:
3765682
MDL number:
MFCD00065473
UNSPSC Code:
12161700

Key Documents

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biological source

synthetic

Quality Level

400

product line

EMPROVE® EVOLVE

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin and microbial; tested

useful pH range

5.5-6.7
5.5-6.7

pKa 

6.1
6.1

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

storage temp.

2-30°C

SMILES string

[Na+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

InChI key

IRHWMYKYLWNHTL-UHFFFAOYSA-M

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Application

MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
0000330636
0000330636
0000330629
0000330629
0000330640

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