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90335

Sigma-Aldrich

Triethylamine

BioUltra, ≥99.5% (GC)

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Synonym(s):
N,N-Diethylethanamine
Linear Formula:
(C2H5)3N
CAS Number:
Molecular Weight:
101.19
Beilstein:
605283
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

vapor density

3.5 (vs air)

Quality Level

vapor pressure

51.75 mmHg ( 20 °C)

product line

BioUltra

Assay

≥99.5% (GC)

form

liquid

autoignition temp.

593 °F

shelf life

36 mo.

expl. lim.

8 %

technique(s)

ion chromatography: suitable

impurities

insoluble matter, passes filter test
≤0.5% water

evapn. residue

≤0.003%

refractive index

n20/D 1.401 (lit.)

pH

12.7 (15 °C, 100 g/L)

bp

88.8 °C (lit.)

mp

−115 °C (lit.)

density

0.726 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.2 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.1 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.02 mg/kg
Na: ≤0.5 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

absorption

cut-off at 278 nm

storage temp.

2-8°C

SMILES string

CCN(CC)CC

InChI

1S/C6H15N/c1-4-7(5-2)6-3/h4-6H2,1-3H3

InChI key

ZMANZCXQSJIPKH-UHFFFAOYSA-N

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General description

Triethyl amine (TEA) is an aliphatic tertiary amine.

Application

Triethylamine has been used to bind the n-hydroxysuccinimide (NHS) group with the amino-treated tip surface. It has also been used as a basic catalyst for acylation.

Biochem/physiol Actions

Triethylamine (TEA) may play a dual role as a base and a solubilizing agent for promoting the reaction in toluene and TEA.
Triethylamine, a mobile-phase modifier, is used in the reversed-phase high-performance liquid chromatography (RP-HPLC) separation of acidic, basic, and neutral molecules. It improves the resolution of amino acids and amino acids amides by suppressing the tailing and the stability of drugs and other compounds.

Other Notes

Component of volatile buffer system in ion-exchange HPLC of oligonucleotides

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

12.2 °F

Flash Point(C)

-11 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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J M Munholland et al.
Analytical biochemistry, 178(2), 320-323 (1989-05-01)
A volatile buffer has been adapted for use with ion-exchange high-performance liquid chromatography in the analysis and preparation of oligonucleotides. The system employs a commercial weakly basic anion-exchange column containing a DEAE-derivatized silica gel and eluted with a volatile buffer
Javier Sotres et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 9(4), 590-599 (2008-02-26)
Atomic force microscopy is a technique capable to study biological recognition processes at the single-molecule level. In this work we operate the AFM in a force-scan based mode, the jumping mode, where simultaneous topographic and tip-sample adhesion maps are acquired.
Sumanta Kumar Padhi et al.
Inorganic chemistry, 51(15), 8091-8102 (2012-07-26)
Cyclometalated ruthenium complexes having C(^)N and N(^)C type coordinating ligands with NAD(+)/NADH function have been synthesized and characterized by spectroscopic methods. The variation of the coordinating position of σ-donating carbon atom leads to a drastic change in their properties. Both
Kai Morino et al.
Scientific reports, 5, 8953-8953 (2015-05-21)
Well-trained clinicians may be able to provide diagnosis and prognosis from very short biomarker series using information and experience gained from previous patients. Although mathematical methods can potentially help clinicians to predict the progression of diseases, there is no method
Hannah Coyle et al.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 23(4), 335-359 (2014-07-08)
The aim of this study was to assess the efficacy of cognitive training, specifically computerized cognitive training (CCT) and virtual reality cognitive training (VRCT), programs for individuals living with mild cognitive impairment (MCI) or dementia and therefore at high risk

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