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Merck
CN

93328

Trizma® maleate

BioUltra, ≥99.5% (NT)

Synonym(s):

TRIS maleate salt, Tris(hydroxymethyl)aminomethane maleate salt, Tromethamine maleate salt

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About This Item

Linear Formula:
NH2C(CH2OH)3 · C4H4O4
CAS Number:
Molecular Weight:
237.21
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161700
EC Number:
276-455-6
MDL number:
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product line

BioUltra

Quality Segment

assay

≥99.5% (NT)

form

powder or crystals

impurities

insoluble matter, passes filter test

ign. residue (900 °C)

≤0.1% (as SO4)

pH

3.0-4.5 (25 °C, 0.5 M in H2O)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

absorption

cut-off at 328 nm in H2O at 0.5 M

SMILES string

NC(CO)(CO)CO.OC(=O)\C=C/C(O)=O

InChI

1S/C4H11NO3.C4H4O4/c5-4(1-6,2-7)3-8;5-3(6)1-2-4(7)8/h6-8H,1-3,5H2;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

HTMWOUBCEZXSHN-BTJKTKAUSA-N

Application

Trizma is used in the formulation of buffer solutions in the pH range between 7.5 and 8.5. Tris buffer solutions are widely used in cell and molecular biology for processes such as protein and nucleic acid extraction and purification. Trizma based buffers are also in column chromatography and in gel electrophoresis. Trizma maleate is used in the preparation of Tris maleate buffers with lower effective pH buffering capacity than Tris buffers. Tris maleate buffers may be used in various grow media, in tissue preparations and as a diluent or washing buffer.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany


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flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

target_organs

Central nervous system

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 1 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



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