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Merck
CN

93851

DL-o-Tyrosine

≥96.0% (NT), suitable for HPLC

Synonym(s):

(±)-2-Amino-3-(2-hydroxyphenyl)propionic acid, 3-(2-Hydroxyphenyl)-DL-alanine

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About This Item

Empirical Formula (Hill Notation):
C9H11NO3
CAS Number:
2370-61-8
Molecular Weight:
181.19
Beilstein:
2805789
EC Number:
219-134-8
MDL number:
MFCD00021725
UNSPSC Code:
12352209
PubChem Substance ID:
329770279
NACRES:
NA.26

Key Documents

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Product Name

DL-o-Tyrosine, ≥96.0% (NT)

Assay

≥96.0% (NT)

form

powder

technique(s)

HPLC: suitable

color

white to faint brown

mp

~260 °C (dec.)

application(s)

peptide synthesis

SMILES string

NC(Cc1ccccc1O)C(O)=O

InChI

1S/C9H11NO3/c10-7(9(12)13)5-6-3-1-2-4-8(6)11/h1-4,7,11H,5,10H2,(H,12,13)

InChI key

WRFPVMFCRNYQNR-UHFFFAOYSA-N

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Related Categories

Biochem/physiol Actions

ortho-Tyrosine (o-Tyrosine), an isomer of standard p-tyrosine, is a phenylalanine oxidation product used as an amino acid oxidation stress marker in analytical procedures such as HPLC and LC-ESI-MS/MS.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG3464
BCCB6452
BCBP1065V

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K Syslová et al.
Journal of breath research, 4(1), 017104-017104 (2010-01-07)
The sensitive assay method was developed for a parallel, rapid and precise determination of the most prominent oxidative stress biomarkers: 8-iso-prostaglandin F(2α) a lipid oxidation biomarker, o-tyrosine an amino acid oxidation biomarker and 8-hydroxy-2'-deoxy-guanosine a nucleic acid oxidation biomarker. The
Gergõ A Molnár et al.
Kidney international, 68(5), 2281-2287 (2005-10-14)
Phenylalanine is converted to para- and ortho-tyrosine by hydroxyl free radical, or to para-tyrosine by the phenylalanine hydroxylase enzyme. The aim of this study was to measure para- and ortho-tyrosine in the urine and plasma of patients with chronic renal
Rachael A Dunlop et al.
The Biochemical journal, 435(1), 207-216 (2011-01-08)
Cellular deposits of oxidized and aggregated proteins are hallmarks of a variety of age-related disorders, but whether such proteins contribute to pathology is not well understood. We previously reported that oxidized proteins form lipofuscin/ceroid-like bodies with a lysosomal-type distribution and
P Dandona et al.
Circulation, 101(2), 122-124 (2000-01-19)
The purpose of this study was to test whether carvedilol has an antioxidant effect in humans in vivo. We administered 3.125 mg of carvedilol twice daily to normal subjects for 1 week. ROS generation by polymorphonuclear leukocytes and mononuclear cells
C H Magsino et al.
Metabolism: clinical and experimental, 49(6), 799-803 (2000-07-06)
We have examined the effect of short-term triiodothyronine (T3) administration on reactive oxygen species (ROS) generation by leukocytes in 9 euthyroid subjects. At a dose of 60 microg/d orally for 7 days, T3 induced a significant increase in ROS generation
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Chromatograms

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