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About This Item
Empirical Formula (Hill Notation):
C22H33N7O8
CAS Number:
Molecular Weight:
523.54
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥97% (HPLC)
form
solid
storage temp.
−20°C
SMILES string
NC(CCCNC(N)=N)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(O)=O)C(=O)NC(CO)C(O)=O
InChI
1S/C22H33N7O8/c23-13(7-4-8-26-22(24)25)18(33)27-14(9-12-5-2-1-3-6-12)19(34)28-15(10-17(31)32)20(35)29-16(11-30)21(36)37/h1-3,5-6,13-16,30H,4,7-11,23H2,(H,27,33)(H,28,34)(H,29,35)(H,31,32)(H,36,37)(H4,24,25,26)
InChI key
SAGYNNXCQOFQHW-UHFFFAOYSA-N
Biochem/physiol Actions
Blocks integrin-binding and nonbinding of fibronectin fragments
Other Notes
Peptide analog of Arg-Gly-Asp-Ser
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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G A Homandberg et al.
Archives of biochemistry and biophysics, 310(1), 40-48 (1994-04-01)
We have reported that Fn fragments (Fn-f), which have been detected in synovial fluids of osteoarthritis and rheumatoid arthritis patients, can potently cause cartilage chondrolysis and depress proteoglycan (PG) synthesis in cartilage tissue cultured as explants. Amino-terminal 29-kDa, gelatin-binding 50-kDa
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