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A3261

Arg-Arg β-naphthylamide trihydrochloride

Name: Arg-Arg &#946;-naphthylamide trihydrochloride
Brand: SIGMA

≥99% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₃N₉O₂ · 3HCl

CAS Number:

100900-26-3

Molecular Weight:

564.94

UNSPSC Code:

12352204

PubChem Substance ID:

24890755

NACRES:

NA.32

MDL number:

MFCD00058045

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Product Name

Arg-Arg β-naphthylamide trihydrochloride,

assay

≥99% (HPLC)

Quality Level

200

form

powder

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl.Cl.Cl.N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C22H33N9O2.3ClH/c23-17(7-3-11-28-21(24)25)19(32)31-18(8-4-12-29-22(26)27)20(33)30-16-10-9-14-5-1-2-6-15(14)13-16;;;/h1-2,5-6,9-10,13,17-18H,3-4,7-8,11-12,23H2,(H,30,33)(H,31,32)(H4,24,25,28)(H4,26,27,29);3*1H/t17-,18-;;;/m0.../s1

InChI key

RNVXXFQJTJQVER-NCXIRTITSA-N

General description

Arg-Arg β-naphthylamide is a dipeptide and a β-naphthylamide derivative.

Substrate for dipeptidyl aminopeptidase III.

Application

Arg-Arg β-naphthylamide trihydrochloride has been used as a substrate for the enzyme dipeptidyl peptidase 3 expressed in human embryonic kidney cells (HEK293T) and as a substrate for peptidase from black-pigmented bacteroides (BPB) and spirochetes.

pictograms

GHS08

signalword

Warning

hcodes

H351

pcodes

P281

Hazard Classifications

Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Identification of periodontopathic bacteria based upon their peptidase activities.

H Suido et al.

Advances in dental research, 2(2), 304-309 (1988-11-01)

Mammalian lens dipeptidyl aminopeptidase III.

A A Swanson et al.

Biochemical and biophysical research communications, 84(4), 1151-1159 (1978-10-30)

Dipeptidyl arylamidase III of the pituitary. Purification and characterization.

S Ellis et al.

The Journal of biological chemistry, 242(20), 4623-4629 (1967-10-25)

Dipeptidyl-aminopeptidases and aminopeptidases in Dictyostelium discoideum.

S A Chan et al.

Biochemical and biophysical research communications, 127(3), 962-968 (1985-03-29)

Extracts prepared from culminating cells of Dictyostelium discoideum have been found to contain dipeptidyl-aminopeptidases I (EC 3.4.14.1), II (EC 3.4.14.2), III (EC 3.4.14.4), arginine aminopeptidase (EC 3.4.11.6) and valine aminopeptidase. Dipeptidyl-aminopeptidase III was the most active of the dipeptidyl-aminopeptidases; its

A rapid assay for dipeptidyl aminopeptidase III in human erythrocytes.

T H Jones et al.

Analytical biochemistry, 119(2), 418-423 (1982-01-15)

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Global Trade Item Number

SKU	GTIN
A3261-5MG	04061832912790
A3261-250MG	04061832912783

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