B3770
(+)-Biotinamidohexanoic acid hydrazide
≥90% (TLC), powder
Synonym(s):
(+)-Biotin-ε-aminocaproyl hydrazide, (+)-Biotin-X-hydrazide, (+)-Biotinamidocaproyl hydrazide, BACH, N-(+)-Biotinyl-6-aminohexanoic hydrazide
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About This Item
Empirical Formula (Hill Notation):
C16H29N5O3S
CAS Number:
Molecular Weight:
371.50
UNSPSC Code:
12352125
eCl@ss:
34058011
PubChem Substance ID:
NACRES:
NC.07
MDL number:
Assay:
≥90% (TLC)
Form:
powder
Quality Level
assay
≥90% (TLC)
form
powder
solubility
DMSO: 25 mg/mL
storage temp.
2-8°C
SMILES string
[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NN)[C@@]1([H])NC(=O)N2
InChI
1S/C16H29N5O3S/c17-21-14(23)8-2-1-5-9-18-13(22)7-4-3-6-12-15-11(10-25-12)19-16(24)20-15/h11-12,15H,1-10,17H2,(H,18,22)(H,21,23)(H2,19,20,24)/t11-,12-,15-/m0/s1
InChI key
IJJWOSAXNHWBPR-HUBLWGQQSA-N
Application
Biotinylation reagent with aminocaproic spacer for aldehyde groups (e.g., periodate-oxidized sugars) and carboxylic acids. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone bond formation.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Kimberly MacKay et al.
Briefings in functional genomics, 19(4), 292-308 (2020-05-01)
The advent of high-resolution chromosome conformation capture assays (such as 5C, Hi-C and Pore-C) has allowed for unprecedented sequence-level investigations into the structure-function relationship of the genome. In order to comprehensively understand this relationship, computational tools are required that utilize
S Spiegel et al.
Journal of immunology (Baltimore, Md. : 1950), 127(2), 572-575 (1981-08-01)
Biotin hydrazide was attached covalently to the aldehyde groups produced by periodate oxidation of bovine brain gangliosides. These modified gangliosides were incorporated into mature rat thymocytes by incubation of the biotinyl gangliosides in the culture medium containing these cells. Avidin
M B Rosenberg et al.
Journal of neurochemistry, 46(2), 641-648 (1986-02-01)
beta-nerve growth factor (NGF) was modified by biotinylation via carboxyl group substitution (C-bio-NGF) using biotin hydrazide and the coupling reagent 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide, under reaction conditions that yielded an average of 3 biotin additions per NGF subunit. NGF was also biotinylated through
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B3770-250MG | 04061833287323 |
| B3770-100MG | 04061833287316 |
| B3770-25MG | 04061833287330 |