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Merck
CN

C106

CGS-12066 maleate salt

solid

Synonym(s):

7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt

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About This Item

Empirical Formula (Hill Notation):
C17H17F3N4 · C4H4O4
CAS Number:
1350965-83-1
Molecular Weight:
450.41
NACRES:
NA.77
PubChem Substance ID:
24277765
UNSPSC Code:
12352200
MDL number:
MFCD01529924

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InChI

1S/C17H17F3N4.C4H4O4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16;5-3(6)1-2-4(7)8/h2-6,11H,7-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES string

OC(=O)\C=C/C(O)=O.CN1CCN(CC1)c2nc3cc(ccc3n4cccc24)C(F)(F)F

InChI key

ZBPAHEUAJMCLRD-BTJKTKAUSA-N

form

solid

color

white

solubility

H2O: 1.4 mg/mL, ethanol: 1.8 mg/mL, 0.1 M HCl: 4 mg/mL

Gene Information

human ... HTR1B(3351)

Biochem/physiol Actions

5-HT1B serotonin receptor agonist.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
108H4731
097H4720

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Understanding nanoparticle interactions with the central nervous system, in particular the blood-brain barrier, is key to advances in therapeutics, as well as assessing the safety of nanoparticles. Challenges in achieving insights have been significant, even for relatively simple models. Here
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