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C4930

γ-Cyclodextrin

Name: γ-Cyclodextrin
Brand: SIGMA

powder, BioReagent, suitable for cell culture, ≥98%

Synonym(s):

Cyclomaltooctaose, Cyclooctaamylose, Schardinger γ-Dextrin

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About This Item

Empirical Formula (Hill Notation):

C₄₈H₈₀O₄₀

CAS Number:

17465-86-0

Molecular Weight:

1297.12

UNSPSC Code:

12352201

NACRES:

NA.77

PubChem Substance ID:

24892741

EC Number:

241-482-4

Beilstein/REAXYS Number:

78740

MDL number:

MFCD00009595

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product line

BioReagent

Quality Level

200

assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

1 M NaOH: 25 mg/mL, clear to slightly hazy

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@]1(O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@@H]2[C@@H](COC(C)=O)O[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O

InChI

1S/C48H80O40/c49-1-9-33-17(57)25(65)41(73-9)82-34-10(2-50)75-43(27(67)19(34)59)84-36-12(4-52)77-45(29(69)21(36)61)86-38-14(6-54)79-47(31(71)23(38)63)88-40-16(8-56)80-48(32(72)24(40)64)87-39-15(7-55)78-46(30(70)22(39)62)85-37-13(5-53)76-44(28(68)20(37)60)83-35-11(3-51)74-42(81-33)26(66)18(35)58/h9-72H,1-8H2/t9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-/m1/s1

InChI key

GDSRMADSINPKSL-HSEONFRVSA-N

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Related Categories

Cell Culture & Analysis

Molecular Biology & Functional Genomics

Supplements for Cell Culture

General description

Cyclodextrins belongs to the family of cyclic α-1,4-glucans and is made of glucose units. This molecule has a shape of a hollow cone. It possesses a hydrophilic external and hydrophobic internal surface, because of which cyclodextrins can form inclusion complexes. γ-Cyclodextrin is extensively used in food and pharmaceutical industries. Cyclodextrins are obtained by the enzymatic conversion of starch/starch derivatives by cyclodextrin glycosyltransferase.

Application

A molecule used to solublize non-polar molecules such a cholesterol for use in cell culture.

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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γ-Cyclodextrin: a review on enzymatic production and applications.

Li, Zhaofeng et al.

Applied Microbiology and Biotechnology, 77(2), 245-245 (2007)

Supramolecular hydrogels formed by pyrene-terminated poly(ethylene glycol) star polymers through inclusion complexation of pyrene dimers with γ-cyclodextrin.

Bin Chen et al.

Chemical communications (Cambridge, England), 48(45), 5638-5640 (2012-04-26)

Novel supramolecular hydrogels were formed between pyrene-terminated poly(ethylene glycol) star polymers and γ-cyclodextrin (γ-CD), through the inclusion complexation of dimers of the pyrene terminals with γ-CD, where γ-CD was directly used as a supramolecular cross-linking reagent without any modification.

Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization.

Takaaki Harada et al.

The journal of physical chemistry. B, 115(5), 1268-1274 (2011-01-05)

Diamide linked γ-cyclodextrin (γ-CD) dimers are used to capture curcumin and suppress its decomposition in water. In this study, succinamide and urea linked γ-CD dimers joined through the C6(A) carbon on each γ-CD are used. The γ-CD dimers, 66γCD(2)su and

Formation of a polypseudorotaxane via self-assembly of γ-cyclodextrin with poly(N-isopropylacrylamide).

Jin Wang et al.

Macromolecular rapid communications, 33(13), 1143-1148 (2012-04-12)

A polypseudorotaxane (PPR) comprising γ-cyclodextrin (γ-CD) as host molecules and poly(N-isopropylacrylamide) (PNIPAM) as a guest polymer is prepared via self-assembly in aqueous solution. Due to the bulky pendant isopropylamide group, PNIPAM exhibits size-selectivity toward self-assembly with α-, β-, and γ-CDs.

yCD/HPyCD mixtures as solubilizer: solid-state characterization and sample dexamethasone eye drop suspension.

Phatsawee Jansook et al.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 13(3), 336-350 (2010-11-26)

Study the complexation of dexamethasone in combinations of γ-cyclodextrin (γCD) and 2-hydroxypropyl-γ-cyclodextrin (HPγCD) with emphasis on solid characterization and development of aqueous dexamethasone eye drop suspension for drug delivery through sclera. Dexamethasone/cyclodextrin (dexamethasone/CD) solid complex systems were prepared and characterized

View All Related Papers

Articles

Cyclodextrin Solubility Table

Cyclodextrin solubilizes fat-soluble vitamins and hormones, enhancing their solubility in water for cell culture applications.

Cyclodextrins

Techniques for solubilizing metabolically important compounds in aqueous solutions are reviewed.

环糊精

很多重要的代谢化合物，例如脂溶性维生素和激素，在水溶液中的溶解度很低。很多技术被用于提高这些化合物在组织培养物、细胞培养物或其他水基应用中的溶解度。

Global Trade Item Number

SKU	GTIN
C4930-100MG	04061833494059
C4930-1G	04061833494066

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