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Merck
CN

D0875

Dansylglycine

fluorescent amino acid

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About This Item

Empirical Formula (Hill Notation):
C14H16N2O4S
CAS Number:
Molecular Weight:
308.35
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
214-129-7
MDL number:
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form

powder

technique(s)

ligand binding assay: suitable

storage temp.

−20°C

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(O)=O

InChI

1S/C14H16N2O4S/c1-16(2)12-7-3-6-11-10(12)5-4-8-13(11)21(19,20)15-9-14(17)18/h3-8,15H,9H2,1-2H3,(H,17,18)

InChI key

QHFXORCWAQTTGH-UHFFFAOYSA-N

Application

Dansylglycine, an HSA drug site II probe, is used for the differentiation and analysis of specific binding sites on serum albumin. Dansylglycine is used to generate chromophore-modified cyclodextrins for use in chemosensor development.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Eva A Enyedy et al.
Bioorganic & medicinal chemistry, 19(14), 4202-4210 (2011-06-24)
The specific binding of carrier ligands of antidiabetic vanadium(IV) and zinc(II) complexes into drug binding pockets of human serum albumin (HSA) has been investigated via displacement reactions of site markers such as warfarin and dansylglycine by different spectroscopic (fluorescence, circular
J Bramhall
Biochemistry, 25(13), 3958-3962 (1986-07-01)
The amphiphilic fluorescent dye N-[(5-dimethylamino)naphth-1-ylsulfonyl]glycine (dansylglycine) can be used to monitor the magnitude and stability of transmembrane proton gradients. Although freely soluble in aqueous media, the dye readily adsorbs to the surfaces of lipid vesicles. Because membrane-bound dye fluoresces at
Máté Kozsup et al.
Journal of inorganic biochemistry, 204, 110963-110963 (2019-12-25)
Four Co(III) ternary complexes with the composition of [(Co(4 N))2(quin)](ClO4)4 or [(Co(4 N))2(quinS)](ClO4)3, where 4 N = tris(2-aminoethyl)amine (tren) or tris(2-pyridylmethyl)amine (tpa), quinH2 = quinizarin (1,4-dihydroxy-9,10-anthraquinone), quinSH3 = quinizarin-2-sulfonic acid (1,4-dihydroxy-9,10-anthraquinone-2-sulfonic acid), were synthesized, characterized and their human serum albumin (HSA) binding capabilities were also tested. The complexes can



Global Trade Item Number

SKUGTIN
D0875-100MG04061832416090
D0875-250MG04061832416106
D0875-1G04061826059081