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CN

D3126

2-Deoxyribose 5-phosphate sodium salt

≥95% (ICP-AES)

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About This Item

Empirical Formula (Hill Notation):
C5H11O7P · xNa+
CAS Number:
Molecular Weight:
214.11 (free acid basis)
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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biological source

synthetic (inorganic)

Quality Level

assay

≥95% (ICP-AES)

form

powder

color

white to off-white

solubility

H2O: 100 mg/mL, clear, colorless to very faintly yellow

cation traces

Na: 14.0-19.0% (dry basis)

storage temp.

−20°C

SMILES string

[Na].OC(COP(O)(O)=O)C(O)CC=O

InChI

1S/C5H11O7P.Na.H/c6-2-1-4(7)5(8)3-12-13(9,10)11;;/h2,4-5,7-8H,1,3H2,(H2,9,10,11);;

InChI key

VKWGIGKPYXQSGV-UHFFFAOYSA-N

Application

2-Deoxyribose 5-phosphate is used as a substrate to identify, differentiate and characterize deoxyribose-phosphate aldolase(s). It is used for the synthesis of 2′-deoxyribonucleoside building blocks for the synthesis of antisense drugs and antiviral nucleosides.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Anming Wang et al.
Bioprocess and biosystems engineering, 35(5), 857-863 (2012-02-10)
To improve the properties of the immobilised 2-deoxy-D-ribose-5-phosphate aldolase (DERA), unreacted functional groups on support surface were blocked with amino acids. The relative activities of the immobilised enzyme were 144.7 and 141.9% when the post-immobilisation modification was done with Arg
Zhong-Yu You et al.
Journal of industrial microbiology & biotechnology, 40(1), 29-39 (2012-11-28)
A codon-optimized 2-deoxyribose-5-phosphate aldolase (DERA) gene was newly synthesized and expressed in Escherichia coli to investigate its biochemical properties and applications in synthesis of statin intermediates. The expressed DERA was purified and characterized using 2-deoxyribose-5-phosphate as the substrate. The specific
Sanni Voutilainen et al.
Applied microbiology and biotechnology, 104(24), 10515-10529 (2020-11-05)
In this work, deoxyribose-5-phosphate aldolase (Ec DERA, EC 4.1.2.4) from Escherichia coli was chosen as the protein engineering target for improving the substrate preference towards smaller, non-phosphorylated aldehyde donor substrates, in particular towards acetaldehyde. The initial broad set of mutations



Global Trade Item Number

SKUGTIN
D3126-100MG04061832388991
D3126-25MG04061832389011