D4630
2,5-Diphenyloxazole
suitable for liquid scintillation spectrometry
Synonym(s):
DPO, PPO
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About This Item
Empirical Formula (Hill Notation):
C15H11NO
CAS Number:
Molecular Weight:
221.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-181-3
Beilstein/REAXYS Number:
157021
MDL number:
Form:
powder
form
powder
Quality Level
bp
360 °C (lit.)
mp
72-74 °C (lit.)
suitability
suitable for liquid scintillation spectrometry
SMILES string
c1ccc(cc1)-c2cnc(o2)-c3ccccc3
InChI
1S/C15H11NO/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H
InChI key
CNRNYORZJGVOSY-UHFFFAOYSA-N
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General description
2,5-Diphenyloxazole (also known as PPO or p-phenylphenoxazole) is a fluorescent organic compound. It can be also used as an organic scintillator due to its high photoluminescence quantum yield and intriguing luminescent properties. It is widely used as a fluorescent probe or dye in analytical chemistry and biochemistry.
Application
2,5-Diphenyloxazole (PPO) can be used in:
- fluorography techniques for the detection of tritium, tritiated glycopeptides, and 35S labeled proteins.
- liquid scintillation cocktails as primary and secondary fluors.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
386.6 - 393.8 °F - closed cup
flash_point_c
197 - 201 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Two-component molecular materials of 2, 5-diphenyloxazole exhibiting tunable ultraviolet/blue polarized emission, pump-enhanced luminescence, and mechanochromic response
Yan, et al.
Advanced Functional Materials
, 24, 587-594 (2014)
Study of new luminophores for use in modern scintillation cocktails
Janda J, et al.
Journal of Luminescence, 201, 390-396 (2018)
Wavelength dependant quenching of 2, 5-diphenyloxazole fluorescence by nucleotides
KrishnaMurthy NV, et al.
Journal of Fluorescence, 18, 29-34 (2008)
F M Williams et al.
British journal of clinical pharmacology, 22(3), 263-268 (1986-09-01)
As a substrate for human liver microsomes, ethoxyresorufin appears to be metabolised by a group of cytochrome P450 isoenzymes which are inducible by cigarette smoking. Kinetic studies in microsomes from four human livers indicate that only one enzyme component is
J T Ahokas et al.
Pharmacology & toxicology, 61(3), 184-190 (1987-09-01)
The oxidative metabolism of 2,5-diphenyloxazole (PPO) is associated with 3-methylcholanthrene inducible cytochrome P-450. The major metabolite formed has m/z of 237, corresponding to hydroxylated PPO. All the possible hydroxylated metabolites of PPO were synthesized and characterized, enabling the assignment of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D4630-1KG | 04061833565568 |
| D4630-100G | 04061833565551 |
| D4630-500G | 04061833553473 |
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