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D6875

21-Hydroxyprogesterone

Name: 21-Hydroxyprogesterone
Brand: SIGMA

synthetic (organic), ≥97% (HPLC), Mineralocorticoid, powder

Synonym(s):

11-Deoxycorticosterone, 11-Desoxycorticosterone, 21-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-21-ol-3,20-dione, Cortexone, DOC, Desoxycortone, Kendall’s desoxy compound B

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₀O₃

CAS Number:

64-85-7

Molecular Weight:

330.46

NACRES:

NA.77

PubChem Substance ID:

24894056

UNSPSC Code:

12352200

EC Number:

200-596-4

MDL number:

MFCD00003661

Beilstein/REAXYS Number:

2062123

Assay:

≥97% (HPLC)

Form:

powder

Quality level:

200

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Product Name

21-Hydroxyprogesterone, ≥97% (HPLC)

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥97% (HPLC)

form

powder

solubility

ethanol: 50 mg/mL, clear, colorless to very faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CO

InChI

1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

InChI key

ZESRJSPZRDMNHY-YFWFAHHUSA-N

signalword

Warning

hcodes

H351,H373

pcodes

P201 - P308 + P313

Hazard Classifications

Carc. 2 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number

0000504285

0000322093

0000322063

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In vivo reprogramming drives Kras-induced cancer development.

Hirofumi Shibata et al.

Nature communications, 9(1), 2081-2081 (2018-05-29)

The faithful shutdown of the somatic program occurs in the early stage of reprogramming. Here, we examined the effect of in vivo reprogramming on Kras-induced cancer development. We show that the transient expression of reprogramming factors (1-3 days) in pancreatic

Life history constraints explain negative relationship between fish productivity and dissolved organic carbon in lakes.

Nicola Craig et al.

Ecology and evolution, 7(16), 6201-6209 (2017-09-02)

Resource availability constrains the life history strategies available to organisms and may thereby limit population growth rates and productivity. We used this conceptual framework to explore the mechanisms driving recently reported negative relationships between fish productivity and dissolved organic carbon

The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells.

Francesca Zalfa et al.

Cell death & disease, 8(11), e3169-e3169 (2017-11-17)

The fragile X mental retardation protein (FMRP) is lacking or mutated in patients with the fragile X syndrome (FXS), the most frequent form of inherited intellectual disability. FMRP affects metastasis formation in a mouse model for breast cancer. Here we

Proteomic changes driven by urban pollution suggest particulate matter as a deregulator of energy metabolism, mitochondrial activity, and oxidative pathways in the rat brain.

J E Araújo et al.

The Science of the total environment, 687, 839-848 (2019-08-16)

The adverse effects of air pollution have been long studied in the lung and respiratory systems, but the molecular changes that this causes at the central nervous system level have yet to be fully investigated and understood. To explore the

Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31.

Xinliu Li et al.

Molecular microbiology, 103(4), 635-656 (2016-11-22)

Current treatment efforts for fungal infections are hampered by the limited availability of antifungal drugs and by the emergence of drug resistance. A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90. Hsp90

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Global Trade Item Number

SKU	GTIN
D6875-1G	04061826236437
D6875-500MG	04061832856308
D6875-5G	04061832856315

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