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Merck
CN

D6898

Deoxyribonucleic acid sodium salt from herring testes

Type XIV

Synonym(s):

DNA

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About This Item

CAS Number:
UNSPSC Code:
41106305
eCl@ss:
32160414
NACRES:
NA.51
MDL number:
Form:
solid
Solubility:
water: 2 mg/mL, clear to hazy, colorless
Storage temp.:
2-8°C
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type

Type XIV

Quality Level

form

solid

color

white

solubility

water: 2 mg/mL, clear to hazy, colorless

storage temp.

2-8°C

General description

Deoxyribonucleic acid sodium salt from herring testes, also known as HtDNA is a natural source of DNA designed for DNA binding agent studies. The detection limits of HtDNA are around 5.0ng and linear ranges of light scattering intensity (I(LS)) is 0.05-2.5 mµg.

Application

Deoxyribonucleic acid sodium salt from herring testes is used in studies of DNA binding agents that modulate DNA structure and function. Herring testes DNA is also used in physicochemical studies of DNA behavior in solution.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料

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X Du et al.
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
Larisa I Labzin et al.
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
Assaf Marcus et al.
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing



Global Trade Item Number

SKUGTIN
D6898-1G04061826761694
D6898-250MG04061833587966
D6898-10G04061833587959