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Merck
CN

F5883

4-Fluoro-7-nitrobenzofurazan

≥98% (elemental analysis)

Synonym(s):

NBD-F

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About This Item

Empirical Formula (Hill Notation):
C6H2FN3O3
CAS Number:
Molecular Weight:
183.10
UNSPSC Code:
12352100
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1077571
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Quality Level

assay

≥98% (elemental analysis)

mp

52-54 °C (lit.)

fluorescence

λex 380 nm; λem 515 nm (hydrolyzed (esterase))

storage temp.

2-8°C

SMILES string

[O-][N+](=O)c1ccc(F)c2nonc12

InChI

1S/C6H2FN3O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H

InChI key

PGZIDERTDJHJFY-UHFFFAOYSA-N

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Application

Useful for fluorescent labeling of amino acids and amines in HPLC

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Chiaki Aoyama et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 25(1), 63-65 (2009-01-14)
A simple and sensitive determination method for selenomethionine (Se-Met) using an HPLC-fluorescence detection system coupled with an on-line electrochemical reactor has been developed. NBD-F (4-fluoro-7-nitro-2,1,3-benzoxadiazole) was used as the fluorescent derivatization reagent for Se-Met. NBD-Se-Met was separated from NBD-derivatives of
Nasr Y Khalil
Talanta, 80(3), 1251-1256 (2009-12-17)
A fully automated, rapid and highly sensitive HPLC method with automated sample pre-treatment by column-switching system and fluorescence detection has been developed for the trace quantitative determination of the new antidepressant reboxetine (RBX) in human plasma. A simple pre-column derivatization
Yang-Ki Park et al.
Journal of chromatography. A, 1217(20), 3357-3361 (2010-04-13)
Single drop microextraction (SDME) can be in-line coupled with capillary electrophoresis by attaching a drop to the tip of a capillary. With a 2-layer drop comprised of an aqueous basic acceptor phase covered with a thin organic layer, acidic analytes
Yanting Song et al.
Amino acids, 42(5), 1897-1902 (2011-04-21)
A high-performance liquid chromatography method in which fluorescence detection is used for the simultaneous determination of 21 amino acids is proposed. Amino acids were derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) and then separated on a monolithic silica column (MonoClad C18-HS, 150 mm×3
Hua-Ming Tseng et al.
Electrophoresis, 30(8), 1399-1405 (2009-03-26)
A sensitive CE with LIF method has been developed for quantitative analysis of small carbohydrates. In this work, 17 carbohydrates including mono-, di- and oligosaccharides were simultaneously derivatized with 4-fluoro-7-nitrobenzofurazane (NBD-F) via a two-step reaction involving reductive amination with ammonia

Global Trade Item Number

SKUGTIN
F5883-5MG04061833284827
F5883-25MG04061832534701
F5883-50MG04061832534718

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