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About This Item
Empirical Formula (Hill Notation):
C6H14NO8P
CAS Number:
Molecular Weight:
259.15
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
Quality Level
assay
≥98% (TLC)
form
powder
technique(s)
thin layer chromatography (TLC): suitable
impurities
<12% water (Karl Fischer)
color
white to off-white
solubility
water: 50 mg/mL, clear, colorless to light yellow
cation traces
Na: <8.5%
storage temp.
−20°C
SMILES string
[Na].NC(C=O)C(O)C(O)C(O)COP(O)(O)=O
InChI
1S/C6H14NO8P.Na.H/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14;;/h1,3-6,9-11H,2,7H2,(H2,12,13,14);;
InChI key
QSNQAUAPIDIXHB-UHFFFAOYSA-N
Application
Glucosamine 6-phosphate has been used to accelerate enzyme-cleavage of DNA plasmids.
Biochem/physiol Actions
D-Glucosamine 6-phosphate, the natural form of glucosamine, is a monosaccharide produced during hexosamine biosynthesis pathway
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Shota Atsumi et al.
Molecular systems biology, 6, 449-449 (2010-12-24)
Escherichia coli has been engineered to produce isobutanol, with titers reaching greater than the toxicity level. However, the specific effects of isobutanol on the cell have never been fully understood. Here, we aim to identify genotype-phenotype relationships in isobutanol response.
Adrian R Ferré-D'Amaré
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 366(1580), 2942-2948 (2011-09-21)
The glmS ribozyme-riboswitch is the first known example of a naturally occurring catalytic RNA that employs a small molecule as a coenzyme. Binding of glucosamine-6-phosphate (GlcN6P) activates self-cleavage of the bacterial ribozyme, which is part of the mRNA encoding the
Jared H Davis et al.
Biochemistry, 50(33), 7236-7242 (2011-07-21)
The glmS riboswitch regulates gene expression through a self-cleavage activity. The reaction is catalyzed with the assistance of the metabolite cofactor glucosamine-6-phosphate (GlcN6P), whose amino group is proposed to serve as the general acid during the reaction. This reaction is
Krista M Brooks et al.
Biochemistry, 50(13), 2424-2433 (2011-03-15)
The glmS ribozyme is a conserved riboswitch found in numerous Gram-positive bacteria and responds to the cellular concentrations of glucosamine 6-phosphate (GlcN6P). GlcN6P binding promotes site-specific self-cleavage in the 5' UTR of the glmS mRNA, resulting in downregulation of gene
Pavel Banás et al.
The journal of physical chemistry. B, 114(26), 8701-8712 (2010-06-12)
The glmS catalytic riboswitch is part of the 5'-untranslated region of mRNAs encoding glucosamine-6-phosphate (GlcN6P) synthetase (glmS) in numerous gram-positive bacteria. Binding of the cofactor GlcN6P induces site-specific self-cleavage of the RNA. However, the detailed reaction mechanism as well as
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G4878-5G | 04061832389899 |
| G4878-100MG | 04061832389882 |
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