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Merck
CN

G6503

4-Guanidinobutyric acid

≥98%, for peptide synthesis

Synonym(s):

γ-Guanidinobutyric acid

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About This Item

Linear Formula:
NH=C(NH2)NHCH2CH2CH2COOH
CAS Number:
Molecular Weight:
145.16
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
207-331-1
MDL number:
Beilstein/REAXYS Number:
1766447
eCl@ss:
32160406
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Product Name

4-Guanidinobutyric acid, ≥98%

Quality Level

assay

≥98%

form

powder or chunks

technique(s)

drug transporter assay: suitable

color

white

mp

280-282 °C

storage temp.

2-8°C

SMILES string

NC(=N)NCCCC(O)=O

InChI

1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)

InChI key

TUHVEAJXIMEOSA-UHFFFAOYSA-N

Application

Gamma-Guanidinobutyric acid (4-GBA) is used to study intestinal transport by the human proton-coupled amino acid transporter(s) (hPAT1). 4-GBA is used with other model compounds such as 1,6-diaminohexane, 1,6-diguanidinohexane, and 1,6-di(cyanoguanidino)hexane to study the biodegradability of the biocide polyhexamethylene biguanide (PHMB).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Zhipan Zhang et al.
The journal of physical chemistry. B, 109(46), 21818-21824 (2006-07-21)
Dye-sensitized solar cells based on nanocrystalline TiO(2) have been fabricated with an amphiphilic ruthenium sensitizer [Ru (4,4'-dicarboxylic acid-2,2'-bipyridine) (4,4'-bis(p-hexyloxystyryl)-2,2'-bipyridine)(NCS)(2)], coded as K-19, and 4-guanidinobutyric acid (GBA) as coadsorbent. The cells showed a approximately 50 mV increase in open-circuit voltage and
Guanidino compounds in hyperargininemia.
B Marescau et al.
Advances in experimental medicine and biology, 153, 427-434 (1982-01-01)
S Shindo et al.
Research communications in chemical pathology and pharmacology, 54(1), 73-85 (1986-10-01)
Arginine levels diminished markedly in the plasma during starvation, suggesting that plasma arginine level principally depends on food intake. Organ arginine levels were relatively stable except for an extraordinary increase in the pancreas at 96 h. Guanidinoacetic acid decreased dramatically
Disturbed metabolism of guanidino compounds characterized by elevated excretion of beta-guanidinopropionic acid and gamma-guanidinobutyric acid--an effect of vigabatrin treatment?
A Schulze et al.
Journal of inherited metabolic disease, 21(3), 268-271 (1998-08-01)
C Cabella et al.
European journal of biochemistry, 268(4), 940-947 (2001-02-17)
Rat hepatocytes in culture take up [14C]-agmatine by both a high-affinity transport system [KM = 0.03 mM; Vmax = 30 pmol x min x (mg protein)-1] and a low-affinity system. The high-affinity system also transports putrescine, but not cationic amino

Global Trade Item Number

SKUGTIN
G6503-500G-A04061833639245
G6503-100G-A04061838354617
G6503-1G04061826059524
G6503-5G04061833639252
G6503-5G-A04061833639269

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