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Merck
CN

G7502

Guanosine 5′-diphosphoglucose sodium salt

Synonym(s):

GDP-Glc, GDP-Glucose, GDPG

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About This Item

Empirical Formula (Hill Notation):
C16H25N5O16P2
CAS Number:
Molecular Weight:
605.34
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Storage temp.:
−20°C
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storage temp.

−20°C

SMILES string

[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(=O)OC4OC(CO)C(O)C(O)C4O)C(O)C3O)c2N1

InChI

1S/C16H25N5O16P2.Na.H/c17-16-19-12-6(13(28)20-16)18-3-21(12)14-10(26)8(24)5(34-14)2-33-38(29,30)37-39(31,32)36-15-11(27)9(25)7(23)4(1-22)35-15;;/h3-5,7-11,14-15,22-27H,1-2H2,(H,29,30)(H,31,32)(H3,17,19,20,28);;

InChI key

MEXITZOHWLXZKR-UHFFFAOYSA-N

Application

Guanosine 5′-diphosphoglucose (GDP-Glucose) is a nucleotide sugar donor substrate for glucosylation reactions mediated by enzymes called glucosyltransferases. GDP-Glucose provides a source of enzyme-available glucose residues for attachment to a wide range of polysaccharide structures.


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Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品

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Articles

Enzymatic glycosyltransferase specificity challenges the one enzyme-one linkage concept.

Related Content

Glycobiology and Glycoproteomics Brochure


Joana Costa et al.
Journal of bacteriology, 189(5), 1648-1654 (2006-12-26)
The pathway for the synthesis of glucosylglycerate (GG) in the thermophilic bacterium Persephonella marina is proposed based on the activities of recombinant glucosyl-3-phosphoglycerate (GPG) synthase (GpgS) and glucosyl-3-phosphoglycerate phosphatase (GpgP). The sequences of gpgS and gpgP from the cold-adapted bacterium
Paramita Chaudhuri et al.
Biochimica et biophysica acta, 1790(5), 368-374 (2009-03-18)
Purified trehalose-6-phosphate synthase (TPS) of Saccharomyces cerevisiae was effective over a wide range of substrates, although differing with regard to their relative activity. Polyanions heparin and chondroitin sulfate were seen to stimulate TPS activity, particularly when a pyrimidine glucose nucleotide
Aaron H Liepman et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(6), 2221-2226 (2005-01-14)
Glucuronoarabinoxylan, xyloglucan, and galactomannan are noncellulosic polysaccharides found in plant cell walls. All consist of beta-linked glycan backbones substituted with sugar side chains. Although considerable progress has been made in characterizing the structure of these polysaccharides, little is known about



Global Trade Item Number

SKUGTIN
G7502-10MG04061833007327
G7502-25MG04061833007334