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Merck
CN

G7627

Guanosine 5′-monophosphomorpholidate 4-morpholine-N,N′-dicyclohexylcarboxamidine salt

≥90%

Synonym(s):

MDCC

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About This Item

Empirical Formula (Hill Notation):
C14H21N6O8P · C17H31N3O
CAS Number:
7361-07-1
Molecular Weight:
725.77
NACRES:
NA.51
PubChem Substance ID:
329799965
UNSPSC Code:
41106305
MDL number:
MFCD00079328
Assay:
≥90%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless to light yellow
Storage temp.:
−20°C

Key Documents

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biological source

synthetic (organic)

Quality Level

200

assay

≥90%

form

powder

solubility

water: 50 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

C1CCC(CC1)N\C(=N\C2CCCCC2)N3CCOCC3.NC4=NC(=O)c5ncn([C@@H]6O[C@H](COP(O)(=O)N7CCOCC7)[C@@H](O)[C@H]6O)c5N4

InChI

1S/C17H31N3O.C14H21N6O8P/c1-3-7-15(8-4-1)18-17(20-11-13-21-14-12-20)19-16-9-5-2-6-10-16;15-14-17-11-8(12(23)18-14)16-6-20(11)13-10(22)9(21)7(28-13)5-27-29(24,25)19-1-3-26-4-2-19/h15-16H,1-14H2,(H,18,19);6-7,9-10,13,21-22H,1-5H2,(H,24,25)(H3,15,17,18,23)/t;7-,9-,10-,13-/m.1/s1

InChI key

CFNWUGDJWKRMBL-VAMAKUSHSA-N

Application

Guanosine 5′-monophosphomorpholidate may be used to synthesize guanosine diphosphate sugars such as GDP-fucose, GDP-mannose, UDP-galactose, and other more complex sugars nucleotides.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SLCR4245
SLCR4245
SLCQ0051
SLCG8350
SLCC8813

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Evan Mercier et al.
Nucleic acids research, 45(20), 11858-11866 (2017-11-18)
The bacterial signal recognition particle (SRP) is part of the machinery that targets ribosomes synthesizing membrane proteins to membrane-embedded translocons co-translationally. Recognition of nascent membrane proteins occurs by virtue of a hydrophobic signal-anchor sequence (SAS) contained in the nascent chain
Maria Mills et al.
Nucleic acids research, 45(20), 11878-11890 (2017-10-24)
The single-stranded DNA binding protein (SSB) of Escherichia coli plays essential roles in maintaining genome integrity by sequestering ssDNA and mediating DNA processing pathways through interactions with DNA-processing enzymes. Despite its DNA-sequestering properties, SSB stimulates the DNA processing activities of
Qixin Wang et al.
Nucleic acids research, 38(4), 1312-1324 (2009-12-09)
RNA helicases function in numerous aspects of RNA biology. These enzymes are RNA-stimulated ATPases that translocate on RNA and unwind or remodel structured RNA in an ATP-dependent fashion. How ATP and the ATPase cycle fuel the work performed by helicases
Valentin Wittmann et al.
The Journal of organic chemistry, 62(7), 2144-2147 (1997-04-04)
An improved procedure is described for the efficient and high-yield (76-91%) synthesis of nucleoside diphosphate sugars from the readily available nucleoside 5'-monophosphomorpholidate and sugar 1-phosphate in the presence of 1H-tetrazole. Comparative kinetic investigations by means of (31)P NMR spectroscopy with
R L Thomas et al.
Carbohydrate research, 184, 77-85 (1988-12-31)
Benzyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-alpha-D-glucopyranoside was converted into its 4-O-(methylsulfonyl) derivative (2) by treatment with methanesulfonyl chloride in pyridine. Displacement of the methylsulfonyloxy group of 2 with fluoride ion afforded benzyl 2-acetamido-3,6-di-O-benzyl-2,4-dideoxy-4-fluoro-alpha-D-galactopyranosi de, which on hydrogenolysis, followed by acetylation, furnished 2-acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-4-fluoro-D-galactopyranose. Treatment of
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Global Trade Item Number

SKUGTIN
G7627-100MG04061833007341

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