G9512
Gly-Phe β-naphthylamide
crystalline
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About This Item
Empirical Formula (Hill Notation):
C21H21N3O2
CAS Number:
Molecular Weight:
347.41
UNSPSC Code:
12352204
PubChem Substance ID:
MDL number:
form
crystalline
storage temp.
−20°C
SMILES string
NCC(N[C@@H](CC1=CC=CC=C1)C(NC2=CC3=CC=CC=C3C=C2)=O)=O
InChI
1S/C21H21N3O2/c22-14-20(25)24-19(12-15-6-2-1-3-7-15)21(26)23-18-11-10-16-8-4-5-9-17(16)13-18/h1-11,13,19H,12,14,22H2,(H,23,26)(H,24,25)
InChI key
YABDXPBHLDPMOA-UHFFFAOYSA-N
General description
Substrate for cathepsin C
Other Notes
Similar to G 4255, but produced by Sigma.
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S Misquith et al.
European journal of biochemistry, 174(4), 691-697 (1988-07-01)
1. Endocytosis of formaldehyde-treated bovine serum albumin by rat liver sinusoidal cells has been followed by injecting rats with the protein labelled with 125I-tyramine cellobiose (125I-TCfBSA). 125I-TCfBSA is quickly taken up by the liver; the radioactivity present in the organ
M Jadot et al.
European journal of biochemistry, 161(3), 695-700 (1986-12-15)
Yeast invertase, when injected into rats, is endocytosed by the liver, mainly by sinusoidal cells. The work reported here aims at investigating the organelles involved in the intracellular journey of this protein. Experiments were performed on rats injected with 125I-invertase
J Hildreth et al.
Biochemical and biophysical research communications, 139(2), 838-844 (1986-09-14)
Cultured fibroblasts from control individuals and two patients affected with the infantile variant of generalized N-acetylneuraminic acid (NeuAc) storage disease were disrupted by nitrogen cavitation, and the post-nuclear supernatant fractions were subjected to subcellular fractionation on Percoll gradients. Accumulating NeuAc
M Jadot et al.
The Biochemical journal, 225(3), 645-648 (1985-02-01)
The release by glycyl-L-phenylalanine 2-naphthylamide (Gly-L-Phe-2-NNap) of endocytosed invertase associated with the MLP fraction (sum of the M, L and P fractions [de Duve, Pressman, Gianetto, Wattiaux & Appelmans (1955) Biochem. J. 63, 604-617]) of rat liver was investigated and
S Akiyama et al.
Cancer research, 45(3), 1005-1007 (1985-03-01)
The cytotoxic activity against human tumor cells of toxic conjugates of Pseudomonas exotoxin with anti-transferrin receptor antibody or epidermal growth factor was potentiated up to 10 to 20-fold by the calcium antagonists verapamil, D-600, and diltiazem and by the lysosomotropic
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