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H1666

Anti-HOXC4 (N-terminal) antibody produced in rabbit

Name: Anti-HOXC4 (N-terminal) antibody produced in rabbit
Brand: SIGMA

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Homeobox 3E, Anti-Homeobox C4, Anti-Hox-3E CP19

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IF, IP, WB

Citations:

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Properties

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~40 kDa

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

immunoprecipitation (IP): 2.5-5 μg/mL using lysates of HEK-293T cells over-expressing human HOXC4, indirect immunofluorescence: 1-2 μg/mL using paraformaldehyde-fixed HEK-293T cells over-expressing human HOXC4, western blot: 0.5-1 μg/mL using lysates of HEK-293T cells over-expressing human HOXC4

UniProt accession no.

P09017

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HOXC4(3221)
mouse ... Hoxc4(15423)
rat ... Hoxc4(24459)

Description

General description

The Homeobox C4 (HOXC4) is located on the human chromosome at 12q13.13.

Application

Anti-HOXC4 (N-terminal) antibody produced in rabbit may be used in:

immunoblotting
immunoprecipitation
immunofluorescence

Biochem/physiol Actions

Anti-HOXC4 (N-terminal) recognizes human HOXC4 (also known as Hox-3E and CP19).

Homeobox C4 (HOXC4) transcription factor/protein stimulates the action of activation-induced cytosine deaminase (AID). The HOXC4 gene is upregulated due to the estrogen-estrogen receptor complexes. HOXC4 gene is expressed in the proliferating lymphocytes of B-, T- and natural killer (NK) cell lineage. This gene expression is elevated with the progression of lymphoid differentiation.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Preparation Note

Store at –20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

059K4774

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Global Trade Item Number

SKU	GTIN
H1666-25UL	04061837771910
H1666-200UL	04061835678259