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Merck
CN

H1754

DL-β-Hydroxyphenethylamine

Synonym(s):

2-Amino-1-phenylethanol, α-(Aminomethyl)benzyl alcohol, DL-β-Hydroxyphenethylamine, Phenylethanolamine

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About This Item

Linear Formula:
NH2CH2CH(OH)C6H5
CAS Number:
Molecular Weight:
137.18
EC Number:
231-469-1
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
971222
MDL number:
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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

160 °C/17 mmHg (lit.)

mp

56-58 °C (lit.)

format

neat

SMILES string

NCC(O)c1ccccc1

InChI

1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2

InChI key

ULSIYEODSMZIPX-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Qian Wu et al.
Journal of medicinal chemistry, 48(23), 7243-7252 (2005-11-11)
The X-ray structure of human phenylethanolamine N-methyltransferase (hPNMT) complexed with its product, S-adenosyl-L-homocysteine (4), and the most potent inhibitor reported to date, SK&F 64139 (7), was used to identify the residues involved in inhibitor binding. Four of these residues, Val53
F Assimacopoulos-Jeannet et al.
Pflugers Archiv : European journal of physiology, 421(1), 52-58 (1992-05-01)
A beta-adrenergic agonist specific for brown adipose tissue, Ro 16-8714, was administered to control and obese insulin-resistant fa/fa rats and glucose utilisation measured in brown adipose tissue using the euglycaemic hyperinsulinaemic clamp combined with the injection of 2-deoxyglucose. Treatment with
Michail S Davidoff et al.
Histochemistry and cell biology, 124(3-4), 313-323 (2005-07-30)
Catecholamines play functional roles in the mature and developing mammalian testis but the cell types responsible for their local synthesis are still controversially discussed. Here, we demonstrate that four enzymes involved in the biosynthesis of catecholamines, namely, tyrosine hydroxylase (TH)
K M Buller et al.
Neuropharmacology, 49(2), 230-242 (2005-07-05)
In opiate addicts or patients receiving morphine treatment, it has been reported that the immune system is often compromised. The mechanisms responsible for the adverse effects of opioids on responses to infection are not clear but it is possible that
M Weinstock et al.
Neuropharmacology, 43(6), 999-1005 (2002-11-09)
TV-3326 is a novel cholinesterase inhibitor that produces irreversible brain-selective inhibition of monoamine oxidase (MAO)-A and B and has antidepressant-like activity in rats after chronic oral administration. This study determined whether TV-3326 would cause less potentiation than other irreversible MAO-inhibitors

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