H177
2-Hydroxytetradecanoic acid
powder
Synonym(s):
2-Hydroxymyristic acid, DL-α-Hydroxymyristic acid
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About This Item
Empirical Formula (Hill Notation):
C14H28O3
CAS Number:
Molecular Weight:
244.37
EC Number:
219-714-0
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1725369
form
powder
color
white
solubility
DMSO: 4 mg/mL (with heating in a 70°C water bath), H2O: 5 mg/mL
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCCC(O)C(O)=O
InChI
1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-12-13(15)14(16)17/h13,15H,2-12H2,1H3,(H,16,17)
InChI key
JYZJYKOZGGEXSX-UHFFFAOYSA-N
Regulatory Information
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A B Vaandrager et al.
The Journal of biological chemistry, 271(12), 7025-7029 (1996-03-22)
The apical membrane of intestinal epithelial cells harbors a unique isozyme of cGMP-dependent protein kinase (cGK type II) which acts as a key regulator of ion transport systems, including the cystic fibrosis transmembrane conductance regulator (CFTR)-chloride channel. To explore the
M J Nadler et al.
Biochemistry, 32(35), 9250-9255 (1993-09-07)
N-Myristoylation of p56lck, a member of the Src family of protein-tyrosine kinases, is essential for its proper targeting to the plasma membrane. 2-Hydroxymyristic acid (HMA) is an analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA
L A Paige et al.
Biochemistry, 29(46), 10566-10573 (1990-11-20)
The importance of myristoylation for the proper biological functioning of many acylated proteins has generated interest in the enzymes of the myristoylation pathway and their interactions with substrates and inhibitors. Previous observations that S-(2-oxopentadecyl)-CoA, a nonhydrolyzable methylene-bridged analogue of myristoyl-CoA