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H3281

Hematin porcine

Synonym(s):

Ferrihemate, Hematin porcine

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About This Item

Linear Formula:
C34H33N4O5Fe
CAS Number:
15489-90-4
Molecular Weight:
633.49
NACRES:
NA.61
PubChem Substance ID:
24895570
UNSPSC Code:
12352202
EC Number:
239-518-9
MDL number:
MFCD00011615
Form:
powder
Biological source:
Porcine

Key Documents

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biological source

Porcine

Quality Level

200

form

powder

storage temp.

2-8°C

SMILES string

Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C=C)c(C)c(cc1n2)n6[Fe](O)n34)c(C)c5C=C

InChI

1S/C34H34N4O4.Fe.H2O/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);;1H2/q;+3;/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

BMUDPLZKKRQECS-HXFTUNQESA-K

Gene Information

pig ... MCOLOR(100530327)

Application

Hematin porcine has been used as a:
  • polymerase chain reaction (PCR) inhibitor to evaluate its effect on the PowerQuant System used for detecting degraded DNA in samples
  • supplement in Haemophilus test medium to culture Haemophilus influenzae isolates for resistance studies
  • standard to determine the heme coefficient as a part of heme iron analysis using raw beef lung

Hematin was used in a study to test in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. It was also used in a study to test in-vitro bacterial identification using fluorescence spectroscopy with an optical fiber system.

Biochem/physiol Actions

Hematin is a hydroxide of heme. It may be used to treat acute porphyric attacks. Hematin suppresses the hepatic aminolevulinic acid (ALA) function and replenishes cytochrome action by restoring the endogenous heme deficit. Early administration of hematin can prevent irreversible neuronal damage induced due to metabolic disorders.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000542319
0000542319
0000505611
0000495730
0000495753

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Effect of drying temperature on nutritional, functional and pasting propertiesand storage stability of beef lung powder, a prospective protein ingredient for food supplements
Jayawardena S, et al.
LWT--Food Science and Technology, 113315-113315 (2022)
Disorders of Peripheral Nerves
Katirji B
Bradley and Daroff's Neurology in Clinical Practice, 1853-1929 (2022)
Peter Bergman et al.
PloS one, 6(8), e24394-e24394 (2011-09-14)
Statin treatment has been associated with a beneficial outcome on respiratory tract infections. In addition, previous in vitro and in vivo experiments have indicated favorable effects of statins in bacterial infections. The aim of the present study was to elucidate
Muriel Vayssier-Taussat et al.
PLoS pathogens, 6(6), e1000946-e1000946 (2010-06-16)
Bacterial pathogens typically infect only a limited range of hosts; however, the genetic mechanisms governing host-specificity are poorly understood. The alpha-proteobacterial genus Bartonella comprises 21 species that cause host-specific intraerythrocytic bacteremia as hallmark of infection in their respective mammalian reservoirs
Jing Liu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 22(50), 18001-18008 (2016-10-27)
Graphene composites with hemin and gold nanoparticles show a better performance for hydrogen peroxide decomposition compared to that of the three components alone or duplex/hybrid complexes. Our previous studies showed that the morphology of the Au nanoparticles may greatly influence
View All Related Papers

Global Trade Item Number

SKUGTIN
H3281-10G04061833620762
H3281-250MG04061833793039
H3281-1G04061833793022
H3281-5G04061833793046

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