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Merck
CN

H4875

Hexamethyldisilazane

Synonym(s):

HMDS

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About This Item

Linear Formula:
(CH3)3SiNHSi(CH3)3
CAS Number:
999-97-3
Molecular Weight:
161.39
EC Number:
213-668-5
UNSPSC Code:
12352300
PubChem Substance ID:
329815211
Beilstein/REAXYS Number:
635752
MDL number:
MFCD00008259

Key Documents

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assay

≥97% (GC)

form

liquid

refractive index

n20/D 1.407 (lit.)

bp

125 °C (lit.)

storage temp.

2-8°C

SMILES string

C[Si](C)(C)N[Si](C)(C)C

InChI

1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3

InChI key

FFUAGWLWBBFQJT-UHFFFAOYSA-N

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Application

A reagent for the preparation of trimethylsilyl derivatives.

pictograms

FlameSkull and crossbones
GHS02,GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

52.5 °F - closed cup

flash_point_c

11.4 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
089K1677
030K0949
S72097-498
S67712-438
039K1393

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Ashang Luwang Laiva et al.
International journal of pharmaceutics, 483(1-2), 115-123 (2015-02-15)
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Niklas Söderholm et al.
PloS one, 6(9), e24353-e24353 (2011-09-29)
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Claire Yu et al.
Biomaterials, 194, 1-13 (2018-12-19)
Decellularized extracellular matrices (dECMs) have demonstrated excellent utility as bioscaffolds in recapitulating the complex biochemical microenvironment, however, their use as bioinks in 3D bioprinting to generate functional biomimetic tissues has been limited by their printability and lack of tunable physical
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The biocompatibility of a cast porous and with a calcium titanate reaction layer functionalized titanium alloy (Ti-6Al-7Nb) was tested by means of cell culture, and a small (rat) and large animal (sheep) model. The uncoated titanium material served as a
Hexamethyldisilazane-mediated controlled polymerization of alpha-amino acid N-carboxyanhydrides.
Hua Lu et al.
Journal of the American Chemical Society, 129(46), 14114-14115 (2007-10-30)
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