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Merck
CN

H6635

Hydrocortisone 3-(O-carboxymethyl)oxime

synthetic (organic), ≥85% (HPLC), cortisol analog, powder

Synonym(s):

11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 3-(O-carboxymethyl)oxime, 4-Pregnene-11β,17α,21-triol-3,20-dione 3-(O-carboxymethyl)oxime, Cortisol 3-(O-carboxymethyl)oxime

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About This Item

Empirical Formula (Hill Notation):
C23H33NO7
CAS Number:
43188-86-9
Molecular Weight:
435.51
UNSPSC Code:
12352202
PubChem Substance ID:
24895751
NACRES:
NA.77
MDL number:
MFCD00056501
Assay:
≥85% (HPLC)
Form:
powder
Quality level:
100

Key Documents

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Product Name

Hydrocortisone 3-(O-carboxymethyl)oxime,

biological source

synthetic (organic)

Quality Level

100

assay

≥85% (HPLC)

form

powder

solubility

chloroform: methanol (1:1): 20 mg/mL, clear, colorless to light yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(\CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO)=N\OCC(O)=O

InChI

1S/C23H33NO7/c1-21-7-5-14(24-31-12-19(28)29)9-13(21)3-4-15-16-6-8-23(30,18(27)11-25)22(16,2)10-17(26)20(15)21/h9,15-17,20,25-26,30H,3-8,10-12H2,1-2H3,(H,28,29)/b24-14+/t15-,16-,17-,20+,21-,22-,23-/m0/s1

InChI key

WXAWNCDYPXVODT-ZAKIEOBNSA-N

Related Categories

Application

Hydrocortisone 3-(O-carboxymethyl)oxime has been used in fecal steroid hormone processing and analysis.

Biochem/physiol Actions

Hydrocortisone 3-(O-carboxymethyl)oxime is used as the analog of cortisol. It is used to modify the surface of an Au chip.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ7082
MKCW0697
MKCP9001
MKCK6561
MKCG3461

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Development of indirect competitive immuno-assay method using SPR detection for rapid and highly sensitive measurement of salivary cortisol levels
Tahara Y, et al.
Frontiers in Bioengineering and Biotechnology, 2, 15-15 (2014)
Characterization of ovarian steroid patterns in female African lions (Panthera leo), and the effects of contraception on reproductive function
Putman S B, et al.
PLoS ONE, 10(10), e0140373-e0140373 (2015)

Global Trade Item Number

SKUGTIN
H6635-50MG04061832850474

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