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Merck
CN

H9627

Hematoxylin

Synonym(s):

Natural Black 1

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About This Item

Empirical Formula (Hill Notation):
C16H14O6 · xH2O
CAS Number:
517-28-2
Molecular Weight:
302.28 (anhydrous basis)
EC Number:
208-237-3
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
57654281
MDL number:
MFCD00078111
Colour Index Number:
75290
Beilstein/REAXYS Number:
91400

Key Documents

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form

powder

Quality Level

200

technique(s)

titration: suitable

mp

200 °C (dec.) (lit.)

solubility

95% ethanol: 1 mg/mL

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

Gene Information

rat ... Adora1(29290), Adora2a(25369)

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Application

Hematoxylin has been used for staining gastric cancer tissues, myocardial tissue, heart sections and ovarian nuclei.

Biochem/physiol Actions

Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells. Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT4380
SHBT4377
0000512326
0000512326
SHBT3173

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Hematoxylin and eosin staining of intact tissues via delipidation and ultrasound
Li Y, et al.
Scientific Reports, 8(1), 12259-12259 (2018)
Clinical significance and effect of Sam68 expression in gastric cancer
Xiao J, et al.
Oncology Letters, 15(4), 4745-4752 (2018)
In Situ Molecular Pathology and Co-Expression Analyses, 81-131 (2013)
A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy
Liu GS, et al.
Journal of Cellular and Molecular Medicine (2018)
Down-regulation of miR-327 alleviates ischemia/reperfusion-induced myocardial damage by targeting RP105
Yang Y, et al.
Cellular Physiology and Biochemistry, 49(3), 1049-1063 (2018)
View All Related Papers

Global Trade Item Number

SKUGTIN
H9627-5X100G04061833503089
H9627-25G04061835564149
H9627-100G04061833812709

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