I8379
L-Isoleucinol hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C6H15NO · HCl
CAS Number:
Molecular Weight:
153.65
UNSPSC Code:
12352200
MDL number:
storage temp.
−20°C
SMILES string
Cl.CC[C@H](C)[C@H](N)CO
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Derek C Cole et al.
Bioorganic & medicinal chemistry letters, 19(3), 926-929 (2008-12-23)
Accumulation of beta-amyloid (Abeta), produced by the proteolytic cleavage of amyloid precursor protein (APP) by beta- and gamma-secretase, is widely believed to be associated with Alzheimer's disease (AD). Research around the high-throughput screening hit (S)-4-chlorophenylsulfonyl isoleucinol led to the identification
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