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L6402

L-(+)-Lactic acid

Name: <SC>L</SC>-(+)-Lactic acid
Brand: SIGMA

BioXtra, ≥98% (titration)

Synonym(s):

(S)-2-Hydroxypropionic acid, Sarcolactic acid

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About This Item

Empirical Formula (Hill Notation):

C₃H₆O₃

CAS Number:

79-33-4

Molecular Weight:

90.08

UNSPSC Code:

12161700

NACRES:

NA.25

PubChem Substance ID:

24896436

EC Number:

201-196-2

Beilstein/REAXYS Number:

1720251

MDL number:

MFCD00064266

Assay:

≥98% (titration)

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Properties

product line

BioXtra

Quality Level

200

assay

≥98% (titration)

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

solubility

H₂O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

storage temp.

2-8°C

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

Description

Biochem/physiol Actions

L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.

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pictograms

GHS05

signalword

Danger

hcodes

H314

pcodes

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

supp_hazards

EUH071

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming.

Silvia Selleri et al.

Oncotarget, 7(21), 30193-30210 (2016-04-14)

Human mesenchymal stromal cells (MSC) have been shown to dampen immune response and promote tissue repair, but the underlying mechanisms are still under investigation. Herein, we demonstrate that umbilical cord-derived MSC (UC-MSC) alter the phenotype and function of monocyte-derived dendritic

ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.

Melissa M Keenan et al.

PLoS genetics, 11(10), e1005599-e1005599 (2015-10-10)

In order to propagate a solid tumor, cancer cells must adapt to and survive under various tumor microenvironment (TME) stresses, such as hypoxia or lactic acidosis. To systematically identify genes that modulate cancer cell survival under stresses, we performed genome-wide

A common bacterial metabolite elicits prion-based bypass of glucose repression.

David M Garcia et al.

eLife, 5 (2016-12-03)

Robust preference for fermentative glucose metabolism has motivated domestication of the budding yeast Saccharomyces cerevisiae. This program can be circumvented by a protein-based genetic element, the [GAR+] prion, permitting simultaneous metabolism of glucose and other carbon sources. Diverse bacteria can

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Global Trade Item Number

SKU	GTIN
L6402-1G	04061833958797
L6402-5G	04061833958803
L6402-10G	04061833958780