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Merck
CN

M6500

Cysteamine hydrochloride

powder or crystals, ≥98% (titration)

Synonym(s):

β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

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About This Item

Linear Formula:
HSCH2CH2NH2 · HCl
CAS Number:
156-57-0
Molecular Weight:
113.61
NACRES:
NA.51
PubChem Substance ID:
24278088
UNSPSC Code:
41106305
EC Number:
205-858-1
MDL number:
MFCD00012904
Beilstein/REAXYS Number:
3590083
Assay:
≥98% (titration)
Form:
powder or crystals

Key Documents

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Product Name

Cysteamine hydrochloride, ≥98% (titration)

biological source

synthetic (organic)

Quality Level

300

assay

≥98% (titration)

form

powder or crystals

mp

67-71 °C

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

2-8°C

SMILES string

Cl[H].NCCS

InChI

1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H

InChI key

OGMADIBCHLQMIP-UHFFFAOYSA-N

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Biochem/physiol Actions

Cysteamine derived from cysteine degradation is the simplest stable aminothiol. Cysteamine is used in the biosynthesis of coenzyme A (CoA). Cysteamine may be useful in studies on oxidative stress and glycation (transglycating agent). Cysteamine is a substrate useful to study the specificity and kinetics of cysteamine (2-aminoethanethiol) dioxygenase(s) (ADO).

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000437088
0000437088
WXBF5344V
0000397357
0000397357

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Anne-Sophie Racine et al.
Molecular brain, 14(1), 130-130 (2021-08-26)
Somatostatin-expressing interneurons (SOM-INs) are a major subpopulation of GABAergic cells in CA1 hippocampus that receive excitation from pyramidal cells (PCs), and, in turn, provide feedback inhibition onto PC dendrites. Excitatory synapses onto SOM-INs show a Hebbian long-term potentiation (LTP) mediated
Matthieu Lagardère et al.
Scientific reports, 10(1), 19954-19954 (2020-11-19)
Fluorescence live-cell and super-resolution microscopy methods have considerably advanced our understanding of the dynamics and mesoscale organization of macro-molecular complexes that drive cellular functions. However, different imaging techniques can provide quite disparate information about protein motion and organization, owing to
Ca Leisinger et al.
Animal reproduction science, 150(1-2), 70-75 (2014-09-28)
The present study utilized a 2×2×2 factorial design examining age (old vs. young), follicle size (≥2mm vs. <2mm) and media supplementation (with or without fetal bovine serum [FBS]) to determine factors that might affect in vitro maturation of alpaca oocytes.
Duncan E Scott et al.
Cell chemical biology, 28(6), 835-847 (2021-03-05)
BRCA2 controls RAD51 recombinase during homologous DNA recombination (HDR) through eight evolutionarily conserved BRC repeats, which individually engage RAD51 via the motif Phe-x-x-Ala. Using structure-guided molecular design, templated on a monomeric thermostable chimera between human RAD51 and archaeal RadA, we
Edward P Harvey et al.
Cell chemical biology, 27(6), 647-656 (2020-05-16)
The BCL-2 family is composed of anti- and pro-apoptotic members that respectively protect or disrupt mitochondrial integrity. Anti-apoptotic overexpression can promote oncogenesis by trapping the BCL-2 homology 3 (BH3) "killer domains" of pro-apoptotic proteins in a surface groove, blocking apoptosis.
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Global Trade Item Number

SKUGTIN
M6500-100G04061834060949
M6500-5G04061831168952
M6500-25G04061834060956

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