M8502
4-Methyl-DL-tryptophan
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About This Item
Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
Molecular Weight:
218.25
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
217-785-2
MDL number:
assay
≥98.0% (TLC)
form
powder
color
off-white to light yellow
storage temp.
2-8°C
SMILES string
Cc1cccc2[nH]cc(CC(N)C(O)=O)c12
InChI
1S/C12H14N2O2/c1-7-3-2-4-10-11(7)8(6-14-10)5-9(13)12(15)16/h2-4,6,9,14H,5,13H2,1H3,(H,15,16)
InChI key
FPJGLSZLQLNZIW-UHFFFAOYSA-N
Biochem/physiol Actions
4-Methyl-DL-tryptophan is a tryptophan derivative that inhibits ATB0,+-specific glycine uptake.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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O J Goddijn et al.
Plant molecular biology, 22(5), 907-912 (1993-08-01)
A novel selection system for plant genetic transformation was developed based on the enzyme tryptophan decarboxylase (TDC; EC 4.1.1.28) from Catharanthus roseus. This enzyme converts the toxic tryptophan analogue 4-methyl tryptophan (4-mT) into the non-toxic compound 4-methyl tryptamine. Expression of
Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy
Karunakaran et al.
Journal of Biochemistry, 414, 343-355 (2008)
Giovanni D'Orazio et al.
Electrophoresis, 40(15), 1966-1971 (2019-02-07)
This work deals with the potentiality of nano liquid chromatography (Nano-LC) for the chiral separation of racemic mixture of tryptophan and some selected derivatives by using 100 µm i.d. fused silica capillary packed with teicoplanin bonded to 5 µm diol silica stationary
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