M9007
Myristoylcholine chloride
90-95%
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About This Item
Linear Formula:
(CH3)3N+CH2CH2OC(O)(CH2)12CH3 Cl-
CAS Number:
Molecular Weight:
349.98
UNSPSC Code:
12352211
PubChem Substance ID:
EC Number:
224-282-1
MDL number:
assay
90-95%
storage temp.
−20°C
SMILES string
Cl.CCCCCCCCCCCCCC(=O)OCC[N](C)(C)C
Application
Myristoylcholine chloride is a fatty acid choline ester with potential use as a skin penetration enhancer for drug delivery.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Yibo Xing et al.
Langmuir : the ACS journal of surfaces and colloids, 28(14), 6032-6036 (2012-03-13)
We have fabricated enzyme responsive polymeric supra-amphiphiles by mixing a block copolymer of poly(ethylene glycol)-block-poly(acrylic acid) with myristoylcholine chloride in water. The polymeric supra-amphiphiles self-assemble into spherical aggregates with sizes varying from about 40 to 150 nm. Moreover, the spherical
Scherlund et al.
Journal of colloid and interface science, 229(2), 365-374 (2000-09-14)
Nonionic cellulose ethers displaying a lower consolute temperature, or cloud-point, close to body temperature were investigated as potential carrier systems for the delivery of local anesthetic agents to the periodontal pocket. The interaction between the polymers, i.e., ethyl(hydroxyethyl)cellulose (EHEC) and
T Loftsson et al.
Acta pharmaceutica Nordica, 1(5), 279-286 (1989-01-01)
Five choline esters, lauroylcholine, myristoylcholine, palmitoylcholine, stearoylcholine and oleoylcholine, were evaluated as skin penetration enhancers by testing their effects on the penetration of six drugs, acyclovir, 17 beta-estradiol, hydrocortisone, nitroglycerin, all-trans-retinoic acid and trifluorothymidine, across hairless mouse skin in vitro