M9503
DL-Methionine DL-sulfoximine
Synonym(s):
DL-(3-Amino-3-carboxypropyl) methyl sulfoximine
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About This Item
Empirical Formula (Hill Notation):
C5H12N2O3S
CAS Number:
Molecular Weight:
180.23
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
217-845-8
MDL number:
storage temp.
2-8°C
SMILES string
CS(=N)(=O)CCC(N)C(O)=O
InChI
1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)
InChI key
SXTAYKAGBXMACB-UHFFFAOYSA-N
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Sherry Dadsetan et al.
Neurochemistry international, 59(4), 482-488 (2011-03-15)
It has been previously demonstrated that ammonia exposure of neurons and astrocytes in co-culture leads to net synthesis not only of glutamine but also of alanine. The latter process involves the concerted action of glutamate dehydrogenase (GDH) and alanine aminotransferase
Clara-Sophie Schwarz et al.
Experimental neurology, 235(1), 368-373 (2012-03-17)
The objective of the present work is to image functional alterations in hepatic encephalopathy (HE) by ammonia-induced changes of in vitro-neuronal network activity and to identify counteracting strategies. Synchronous bursting behavior of rat cortical cells which is the result of
Makoto Ishikawa et al.
Investigative ophthalmology & visual science, 52(9), 6604-6616 (2011-07-22)
PURPOSE. High levels of glutamate can be toxic to retinal GCs. Thus, effective buffering of extracellular glutamate is important in preserving retinal structure and function. GLAST, a major glutamate transporter in the retina, and glutamine synthetase (GS) regulate extracellular glutamate
Y Tsuboi et al.
The European journal of neuroscience, 34(2), 292-302 (2011-06-29)
Previous studies indicate that the astroglial glutamate-glutamine shuttle may be involved in acute pulpal inflammatory pain by influencing central sensitization induced in nociceptive neurons in the trigeminal subnucleus caudalis [the medullary dorsal horn (MDH)] by application of an inflammatory irritant
Renata Novaes et al.
Immunobiology, 218(9), 1166-1174 (2013-05-15)
The human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus associated with neoplasias and inflammatory diseases, such as adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1-infected individuals present a spontaneous T lymphocyte proliferation. This phenomenon is related
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