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About This Item
Linear Formula:
HOOCCH2COCOOH
CAS Number:
Molecular Weight:
132.07
UNSPSC Code:
12352204
NACRES:
NA.75
PubChem Substance ID:
EC Number:
206-329-8
Beilstein/REAXYS Number:
1705475
MDL number:
biological source
synthetic (organic)
Quality Segment
product line
BioReagent
assay
≥97% (HPLC)
form
powder
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable
solubility
H2O: 100 mg/mL
storage temp.
−20°C
SMILES string
OC(=O)CC(=O)C(O)=O
InChI
1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)
InChI key
KHPXUQMNIQBQEV-UHFFFAOYSA-N
General description
Oxaloacetic acid is a dicarboxylic acid that is present in every cell in the body. It is a metabolic intermediate of the tricarboxylic acid (TCA) cycle and gluconeogenesis.
Application
Oxaloacetic acid has been used to evaluate its effect on neuromuscular function and lifespan in amyotrophic lateral sclerosis (ALS) model superoxide dismutase 1 (SOD1) G93A mice. It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) to culture chicken fibroblast (DF-1) cells and chemically immortalized leghorn male hepatoma (LMH) cells for functional validation experiments.
Biochem/physiol Actions
Oxaloacetic acid plays a vital role in central metabolism. It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| O7753-100G | 04061834248521 |
| O7753-5G | 04061835514212 |
| O7753-25G | 04061834248538 |
