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Merck
CN

P3636

Pentobarbital

Synonym(s):

5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal

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About This Item

Empirical Formula (Hill Notation):
C11H18N2O3
CAS Number:
76-74-4
Molecular Weight:
226.27
EC Number:
200-983-8
UNSPSC Code:
12352200
MDL number:
MFCD00057561

Key Documents

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InChI key

WEXRUCMBJFQVBZ-UHFFFAOYSA-N

InChI

1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

SMILES string

CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

drug control

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

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Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
113H0992
059H0868
039F0227
034H0886
033H0504

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Naoe Okamura et al.
Neuropharmacology, 58(1), 166-172 (2009-07-07)
Neuropeptide S (NPS) and its cognate receptor were reported to mediate anxiolytic-like and arousal effects. NPS receptors are predominantly expressed in the brain, especially in limbic structures, including amygdala, olfactory nucleus, subiculum and retrosplenial cortex. In contrast, the NPS precursor
Nassir Mansour et al.
Journal of neurosurgery. Pediatrics, 12(1), 37-43 (2013-05-07)
Barbiturates are widely used in the management of high intracranial pressure (ICP) caused by diffuse brain swelling. The cardiovascular, renal, and immunological side effects of these drugs limit them to last-line therapy. There are few published data regarding the role
M Katayama et al.
Laboratory animals, 47(2), 122-126 (2013-04-09)
Pharmacokinetics of drugs may differ between small and large mammals (including humans); therefore, drug testing in animal models must be carefully designed. Sprague-Dawley rats were used in cardiac experiments, during which the lopinavir concentration in serum had to match human
Brandon H Gilroyed et al.
Journal of veterinary science, 14(1), 103-106 (2013-02-08)
In the event of an infectious disease outbreak in cattle, carcasses must be disposed of in a rapid and contained manner. This brief communication details injection of a barbiturate to euthanize cattle inoculated with Escherichia coli O157:H7 followed by carcass
Maria Pedro Guarino et al.
In vivo (Athens, Greece), 27(1), 127-132 (2012-12-15)
We compared the effects of two different anaesthetics, sodium pentobarbital (65 mg/kg) and ketamine (30 mg/kg) plus xylazine (4 mg/kg) (KX) on insulin sensitivity, fasting glycaemia, insulinaemia and free fatty acids (FFA). Four groups of Wistar rats were used: KX
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