P5648
β-Propiolactone
Grade II, ≥90%
Synonym(s):
Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone
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About This Item
Empirical Formula (Hill Notation):
C3H4O2
CAS Number:
Molecular Weight:
72.06
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
200-340-1
MDL number:
Assay:
≥90%
Quality level:
type
Grade II
Quality Level
assay
≥90%
refractive index
n20/D 1.412 (lit.)
bp
162 °C (lit.)
mp
−33 °C (lit.)
density
1.146 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
O=C1CCO1
InChI
1S/C3H4O2/c4-3-1-2-5-3/h1-2H2
InChI key
VEZXCJBBBCKRPI-UHFFFAOYSA-N
General description
β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.
Application
β-Propiolactone has been used for Influenza virus deactivation.
Disclaimer
Insoluble polymers may form during storage.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
158.0 °F - closed cup
flash_point_c
70 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
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Veterinary Immunology-E book, 262-262 (2013)
Vesla I Kullaya et al.
Viral immunology, 30(8), 576-581 (2017-08-08)
Detection of respiratory syncytial virus (RSV) in blood, including mononuclear leukocytes and organs other than the lung, suggests that RSV disseminates outside the respiratory tract. In this study, the role of platelets in host defense against RSV was explored using
Tiago Abreu-Mota et al.
Nature communications, 9(1), 4223-4223 (2018-10-13)
Lassa fever (LF), caused by Lassa virus (LASV), is a viral hemorrhagic fever for which no approved vaccine or potent antiviral treatment is available. LF is a WHO priority disease and, together with rabies, a major health burden in West
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5648-10ML | 04061838164629 |
| P5648-1ML | 04061838164636 |
| P5648-100ML | 04061838164612 |
| P5648-50ML | 04061838114556 |
| P5648-5ML | 04061838092823 |