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P6210

Pyrantel pamoate

BioXtra

Synonym(s):

1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate

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About This Item

Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
22204-24-6
Molecular Weight:
594.68
UNSPSC Code:
51452307
NACRES:
NA.85
PubChem Substance ID:
24898655
EC Number:
244-837-1
Beilstein/REAXYS Number:
9034755
MDL number:
MFCD00072037
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product line

BioXtra

form

powder

impurities

<0.0005% Phosphorus (P), <0.1% Insoluble matter

ign. residue

<0.5%

cation traces

Ca: <0.002%, Al: <0.0005%, Cu: <0.0005%, Fe: <0.001%, K: <0.005%, Mg: <0.0005%, Na: <0.01%, Pb: <0.001%, Zn: <0.0005%

antibiotic activity spectrum

parasites

mode of action

enzyme | inhibits

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

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Application

It is a combination of pyrantel and pamoic acid. It is used to study mechanisms underlying gut dysfunction in a murine model.

Biochem/physiol Actions

Pyrantel pamoate is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SLBV0663
SLBR7047V
SLBN3363V
SLBL4475V
SLBJ9285V

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Kashinath Ghosh et al.
The Journal of infectious diseases, 193(1), 155-162 (2005-12-03)
The effect of concurrent (active) and treated hookworm infections on the immunogenicity of vaccination with the recombinant fusion protein Ay-Ancylostoma-secreted protein 2 was analyzed in the Golden Syrian hamster. Hamsters were infected with the hookworm Ancylostoma ceylanicum and vaccinated with
Education and imaging. Gastrointestinal: ascariasis.
A Suzuki et al.
Journal of gastroenterology and hepatology, 23(11), 1770-1770 (2009-01-06)
Timothy J Smyser et al.
Journal of wildlife diseases, 51(3), 640-650 (2015-05-15)
Baylisascaris procyonis is a common gastrointestinal parasite of raccoons (Procyon lotor) and is a zoonotic helminth with the potential to cause severe or fatal infection. Raccoons thrive in human-dominated landscapes, and the fecal-oral transmission pathway and lack of effective treatment
C A Northrop-Clewes et al.
The American journal of clinical nutrition, 73(1), 53-60 (2000-12-22)
The effect of helminth infestation on the nutrition, growth, and physiology of the host is still poorly understood. Anthelmintic treatment of children in developing countries has had varying success in terms of growth improvements. The objective of this study was
Vinod K Gupta et al.
Journal of colloid and interface science, 350(1), 330-335 (2010-07-21)
Adsorption and electrochemical reduction of pyrantel pamoate are studied in Britton Robinson buffer medium at hanging mercury drop electrode (HMDE) by Adsorptive Stripping Voltammetric technique. The peak current shows a linear dependence with the drug concentration over the range 250
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Global Trade Item Number

SKUGTIN
P6210-5G04061834393047

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